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Notch signaling = immunity and cancer /

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Notch signaling = immunity and cancer /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Notch signaling/ edited by Koji Yasutomo.
Reminder of title:	immunity and cancer /
other author:	Yasutomo, Koji.
Published:	Singapore :Springer Singapore : : 2017.,
Description:	vii, 104 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Notch genes. -
Online resource:	http://dx.doi.org/10.1007/978-981-10-4971-2
ISBN:	9789811049712

Notch signaling = immunity and cancer /
Notch signalingimmunity and cancer /[electronic resource] :edited by Koji Yasutomo. - Singapore :Springer Singapore :2017. - vii, 104 p. :ill., digital ;24 cm.

Preface -- Part I Immunology -- Ch1 Notch ligands for lymphocyte development -- Ch2 Notch controls the differentiation and function of cytotoxic CD8 T cells -- Ch3 Notch and myeloid cells -- Ch4 Taking CD4 T cells up a Notch -- Part II Cancer -- Ch5 NOTCH in malignant lymphoma -- Ch6 The two faces of Notch in solid cancers.

This book covers the broad area related to Notch-mediated regulation of the immune system and tumorigenesis. Notch signaling was originally identified as a crucial pathway to regulate cell fate choice. Subsequent studies, however, have revealed that Notch regulates many steps of immune cell differentiation or development as well as tumorigenesis of cells. Although there are still many controversial issues regarding the functions or regulatory mechanism of Notch, it is important to summarize all data together in one volume to help facilitate this research area. Also, the studies regarding the functions of Notch in immune cells and tumor cells have motivated researchers and pharmaceutical companies to develop drugs for treating immune-mediated diseases and tumors. Therefore, this book covering the broad area of Notch in immunology and tumorigenesis will be attractive to many researchers including faculty members and postdoctoral fellows in academia and researchers in the pharmaceutical industry.

ISBN: 9789811049712

Standard No.: 10.1007/978-981-10-4971-2doiSubjects--Topical Terms:

883050
Notch genes.

LC Class. No.: QP552.N67

Dewey Class. No.: 572.6

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245 0 0 $a Notch signaling $h [electronic resource] : $b immunity and cancer / $c edited by Koji Yasutomo.
260 $a Singapore : $c 2017. $b Springer Singapore : $b Imprint: Springer,
300 $a vii, 104 p. : $b ill., digital ; $c 24 cm.
505 0 $a Preface -- Part I Immunology -- Ch1 Notch ligands for lymphocyte development -- Ch2 Notch controls the differentiation and function of cytotoxic CD8 T cells -- Ch3 Notch and myeloid cells -- Ch4 Taking CD4 T cells up a Notch -- Part II Cancer -- Ch5 NOTCH in malignant lymphoma -- Ch6 The two faces of Notch in solid cancers.
520 $a This book covers the broad area related to Notch-mediated regulation of the immune system and tumorigenesis. Notch signaling was originally identified as a crucial pathway to regulate cell fate choice. Subsequent studies, however, have revealed that Notch regulates many steps of immune cell differentiation or development as well as tumorigenesis of cells. Although there are still many controversial issues regarding the functions or regulatory mechanism of Notch, it is important to summarize all data together in one volume to help facilitate this research area. Also, the studies regarding the functions of Notch in immune cells and tumor cells have motivated researchers and pharmaceutical companies to develop drugs for treating immune-mediated diseases and tumors. Therefore, this book covering the broad area of Notch in immunology and tumorigenesis will be attractive to many researchers including faculty members and postdoctoral fellows in academia and researchers in the pharmaceutical industry.
650 0 $a Notch genes. $3 883050
650 0 $a Notch proteins. $3 1199727
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Immunology. $3 592892
650 2 4 $a Cancer Research. $3 668358
700 1 $a Yasutomo, Koji. $3 1199726
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-981-10-4971-2
950 $a Biomedical and Life Sciences (Springer-11642)

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