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Genome editing in neurosciences

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Genome editing in neurosciences/ edited by Rudolf Jaenisch, Feng Zhang, Fred Gage.
其他作者:	Jaenisch, Rudolf.
出版者:	Cham :Springer International Publishing : : 2017.,
面頁冊數:	xi, 123 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Neurogenetics. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-60192-2
ISBN:	9783319601922

Genome editing in neurosciences
Genome editing in neurosciences[electronic resource] /edited by Rudolf Jaenisch, Feng Zhang, Fred Gage. - Cham :Springer International Publishing :2017. - xi, 123 p. :ill., digital ;24 cm. - Research and perspectives in neurosciences,0945-6082. - Research and perspectives in neurosciences..

Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington's Disease -- Therapeutic gene editing in muscles and muscle stem cells.

Open access.

This book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Medecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.

ISBN: 9783319601922

Standard No.: 10.1007/978-3-319-60192-2doiSubjects--Topical Terms:

582662
Neurogenetics.

LC Class. No.: QP356.22

Dewey Class. No.: 572.8

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