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Heat shock proteins in the immune system

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Heat shock proteins in the immune system/ edited by Robert J. Binder, Pramod K. Srivastava.
其他作者:	Binder, Robert J.
出版者:	Cham :Springer International Publishing : : 2018.,
面頁冊數:	x, 185 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Heat shock proteins. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-69042-1
ISBN:	9783319690421

Heat shock proteins in the immune system
Heat shock proteins in the immune system[electronic resource] /edited by Robert J. Binder, Pramod K. Srivastava. - Cham :Springer International Publishing :2018. - x, 185 p. :ill., digital ;24 cm.

Introduction and history -- Part I: Structure of the HSPs in relation to chaperoning peptides and proteins -- Chapter 1: Hsp70-subsrate interactions -- Chapter 2: Molecular Chaperone Inhibitors -- Part II: Exposure of HSPs to immune cells -- Chapter 3: Extracellular Heat Shock Proteins as Stress Communication Signals -- Part III: Regulation of immune responses by extracellular HSPs -- Chapter 4: The Heat Shock Protein-CD91 pathway and Tumor Immuno-surveillance -- Chapter 5: Bridging the gaps in the vaccine development: Avant-garde vaccine approach with secreted heat shock protein gp96-Ig -- Chapter 6: Regulation of the Extracellular Matrix by Heat Shock Proteins and Molecular Chaperones -- Chapter 7: Heat shock protein mediated T cell responses in pathogen infections -- Chapter 8: An ancestral immune surveillance system in the amphibian Xenopus connecting certain heat shock proteins with classical and nonclassical MHC class I molecules -- Chapter 9: Inhibition of HSPs for Enhanced Immunity.

Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system. This one-stop resource contains numerous images to both help illustrate the research on heat shock proteins, and better clarify the field for the non-expert. Heat shock proteins (HSPs) were discovered in 1962 and were quickly recognized for their role in protecting cells from stress. Twenty years later, the immunogenicity of a select few HSPs was described, and for the past 30 years, these findings have been applied to numerous branches of immunology, including tumor immunology and immunosurveillance, immunotherapy, etiology of autoimmunity, immunotherapy of infectious diseases, and expression of innate receptors. While HSPs can be used to manipulate immune responses by exogenous administration, they appear to be involved in initiation of de novo immune responses to cancer and likely in the maintenance of immune homeostasis.

ISBN: 9783319690421

Standard No.: 10.1007/978-3-319-69042-1doiSubjects--Topical Terms:

582771
Heat shock proteins.

LC Class. No.: QP552.H43 / H438 2018

Dewey Class. No.: 572.6

Heat shock proteins in the immune system
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