國立虎尾科技大學 |

Introduction in synthetic biology = about modeling, computation, and circuit design /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Introduction in synthetic biology/ by Mario Andrea Marchisio.
Reminder of title:	about modeling, computation, and circuit design /
Author:	Marchisio, Mario Andrea.
Published:	Singapore :Springer Singapore : : 2018.,
Description:	xii, 187 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Synthetic biology. -
Online resource:	http://dx.doi.org/10.1007/978-981-10-8752-3
ISBN:	9789811087523

Introduction in synthetic biology = about modeling, computation, and circuit design /
Marchisio, Mario Andrea.

Introduction in synthetic biologyabout modeling, computation, and circuit design /[electronic resource] :by Mario Andrea Marchisio. - Singapore :Springer Singapore :2018. - xii, 187 p. :ill., digital ;24 cm. - Learning materials in biosciences,2509-6125. - Learning materials in biosciences..

Chapter 1: Introduction -- Chapter 2: Modeling: choosing a kinetics -- Chapter 3: Modeling at computer: getting started -- Chapter 4: Stochastic modeling -- Chapter 5: Steady states -- Chapter 6: Stability analysis: hysteresis and oscillations -- Chapter7: Toggle switch: dynamics and steady states -- Chapter 8: Rule-based modeling -- Chapter 9: Gene circuit modular computational design -- Chapter 10: Parameter analysis -- Chapter 11: Circuit analysis with COPASI -- Chapter 12: Circuit motifs.

The textbook is based on the lectures of the course "Synthetic Biology" for Master's students in biology and biotechnology at the Harbin Institute of Technology. The goal of the textbook is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab. Concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis and optimization are presented. At the end of the textbook, a chapter contains a description of structural motifs (e.g. positive and negative feedback loops, Boolean gates) that carry out specific functions and can be combined into larger networks. Moreover, several chapters show how to build up (an analyse, where possible) models for synthetic gene circuits with four different open-source software i.e. COPASI, XPPAUT, BioNetGeN, and Parts & Pools-ProMoT.

ISBN: 9789811087523

Standard No.: 10.1007/978-981-10-8752-3doiSubjects--Topical Terms:

787925
Synthetic biology.

LC Class. No.: TA164 / .M373 2018

Dewey Class. No.: 660.6

Introduction in synthetic biology = about modeling, computation, and circuit design /
LDR:02487nam a2200337 a 4500 001 926074
003 DE-He213
005 20181116085829.0
006 m d
007 cr nn 008maaau
008 190625s2018 si s 0 eng d
020 $a 9789811087523 $q (electronic bk.)
020 $a 9789811087516 $q (paper)
024 7 $a 10.1007/978-981-10-8752-3 $2 doi
035 $a 978-981-10-8752-3
040 $a GP $c GP
041 0 $a eng
050 4 $a TA164 $b .M373 2018
072 7 $a MQW $2 bicssc
072 7 $a MED003040 $2 bisacsh
072 7 $a MED009000 $2 bisacsh
082 0 4 $a 660.6 $2 23
090 $a TA164 $b .M317 2018
100 1 $a Marchisio, Mario Andrea. $3 1204330
245 1 0 $a Introduction in synthetic biology $h [electronic resource] : $b about modeling, computation, and circuit design / $c by Mario Andrea Marchisio.
260 $a Singapore : $c 2018. $b Springer Singapore : $b Imprint: Springer,
300 $a xii, 187 p. : $b ill., digital ; $c 24 cm.
490 1 $a Learning materials in biosciences, $x 2509-6125
505 0 $a Chapter 1: Introduction -- Chapter 2: Modeling: choosing a kinetics -- Chapter 3: Modeling at computer: getting started -- Chapter 4: Stochastic modeling -- Chapter 5: Steady states -- Chapter 6: Stability analysis: hysteresis and oscillations -- Chapter7: Toggle switch: dynamics and steady states -- Chapter 8: Rule-based modeling -- Chapter 9: Gene circuit modular computational design -- Chapter 10: Parameter analysis -- Chapter 11: Circuit analysis with COPASI -- Chapter 12: Circuit motifs.
520 $a The textbook is based on the lectures of the course "Synthetic Biology" for Master's students in biology and biotechnology at the Harbin Institute of Technology. The goal of the textbook is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab. Concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis and optimization are presented. At the end of the textbook, a chapter contains a description of structural motifs (e.g. positive and negative feedback loops, Boolean gates) that carry out specific functions and can be combined into larger networks. Moreover, several chapters show how to build up (an analyse, where possible) models for synthetic gene circuits with four different open-source software i.e. COPASI, XPPAUT, BioNetGeN, and Parts & Pools-ProMoT.
650 0 $a Synthetic biology. $3 787925
650 0 $a Bioengineering. $3 598252
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Biomedical Engineering/Biotechnology. $3 1068811
650 2 4 $a Systems Biology. $3 683756
650 2 4 $a Biotechnology. $3 554955
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Learning materials in biosciences. $3 1113322
856 4 0 $u http://dx.doi.org/10.1007/978-981-10-8752-3
950 $a Biomedical and Life Sciences (Springer-11642)