國立虎尾科技大學 |

Glucose-sensing receptor in pancreatic beta-cells

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Glucose-sensing receptor in pancreatic beta-cells/ edited by Itaru Kojima.
other author:	Kojima, Itaru.
Published:	Singapore :Springer Singapore : : 2018.,
Description:	v, 71 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Glucose - Receptors. -
Online resource:	http://dx.doi.org/10.1007/978-981-13-0002-8
ISBN:	9789811300028

Glucose-sensing receptor in pancreatic beta-cells
Glucose-sensing receptor in pancreatic beta-cells[electronic resource] /edited by Itaru Kojima. - Singapore :Springer Singapore :2018. - v, 71 p. :ill., digital ;24 cm.

1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells.

Since the 1970s, there has been much discussion about the "glucoreceptor" and "substrate site" and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the "glucoreceptor theory." This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: "glucoreceptor theory". Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.

ISBN: 9789811300028

Standard No.: 10.1007/978-981-13-0002-8doiSubjects--Topical Terms:

1204400
Glucose
--Receptors.

LC Class. No.: QP702.G56

Dewey Class. No.: 572.565

Glucose-sensing receptor in pancreatic beta-cells
LDR:02303nam a2200313 a 4500 001 926114
003 DE-He213
005 20181116095001.0
006 m d
007 cr nn 008maaau
008 190625s2018 si s 0 eng d
020 $a 9789811300028 $q (electronic bk.)
020 $a 9789811300011 $q (paper)
024 7 $a 10.1007/978-981-13-0002-8 $2 doi
035 $a 978-981-13-0002-8
040 $a GP $c GP
041 0 $a eng
050 4 $a QP702.G56
072 7 $a MFG $2 bicssc
072 7 $a MED075000 $2 bisacsh
082 0 4 $a 572.565 $2 23
090 $a QP702.G56 $b G567 2018
245 0 0 $a Glucose-sensing receptor in pancreatic beta-cells $h [electronic resource] / $c edited by Itaru Kojima.
260 $a Singapore : $c 2018. $b Springer Singapore : $b Imprint: Springer,
300 $a v, 71 p. : $b ill., digital ; $c 24 cm.
505 0 $a 1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells.
520 $a Since the 1970s, there has been much discussion about the "glucoreceptor" and "substrate site" and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the "glucoreceptor theory." This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: "glucoreceptor theory". Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.
650 0 $a Glucose $x Receptors. $3 1204400
650 0 $a Pancreatic beta cells. $3 679777
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Human Physiology. $3 668349
650 2 4 $a Endocrinology. $3 645497
700 1 $a Kojima, Itaru. $3 1204399
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-981-13-0002-8
950 $a Biomedical and Life Sciences (Springer-11642)