國立虎尾科技大學 |

Stem cell genetics for biomedical research = past, present, and future /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Stem cell genetics for biomedical research/ edited by Raul Delgado-Morales.
其他題名:	past, present, and future /
其他作者:	Delgado-Morales, Raul.
出版者:	Cham :Springer International Publishing : : 2018.,
面頁冊數:	xi, 426 p. :digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Stem cells - Research. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-90695-9
ISBN:	9783319906959

Stem cell genetics for biomedical research = past, present, and future /
Stem cell genetics for biomedical researchpast, present, and future /[electronic resource] :edited by Raul Delgado-Morales. - Cham :Springer International Publishing :2018. - xi, 426 p. :digital ;24 cm.

Part I: Stem cells for brain disorders -- Chapter1: Human induced pluripotent stem cell-derived neurons to model and gain insights into Alzheimer's disease pathogenesis -- Chapter2: Modeling schizophrenia with human stem cells -- Chapter3: Rett Syndrome and Stem Cell research -- Chapter4: Stem Cell Applications in Spinal Cord Injury: A Primer -- Chapter5: Cell-Based Therapy for Retinal Degenerative Disease -- Chapter6: Past, present and future of cell based-therapy in progressive multiple sclerosis -- Part II: Stem cells for cardiovascular diseases -- Chapter7: Cardiac Stem Cells: a plethora of potential therapies for myocardial regeneration within reach -- Chapter8: Human Induced Pluripotent Stem Cell-derived Cardiomyocytes in the Evaluation of Cardiotoxic Potential of Drugs -- Part III: Stem cells for general medicine -- Chapter9: Regenerative medicine for diabetes treatment: new β-cell sources -- Chapter10: Dental pulp stem cells promote wound healing and muscle regeneration -- Chapter11: From bench to bedside of mesenchymal Stem Cells use for Rheumatoid Arthritis treatment -- Chapter12: Stem Cells and Cancer -- Chapter13: The relevance of induced pluripotent stem cells for the study of physiological and premature aging -- Part IV: Technical challenges and future -- Chapter14: Pluripotent stem cell banks -- Chapter15: Genetic and Epigenetic engineering: the CRISPR/Cas9 era.

This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer's disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.

ISBN: 9783319906959

Standard No.: 10.1007/978-3-319-90695-9doiSubjects--Topical Terms:

674469
Stem cells
--Research.

LC Class. No.: QH588.S83 / S74 2018

Dewey Class. No.: 616.02774

Stem cell genetics for biomedical research = past, present, and future /
LDR:03778nam a2200325 a 4500 001 926850
003 DE-He213
005 20181227095241.0
006 m d
007 cr nn 008maaau
008 190626s2018 gw s 0 eng d
020 $a 9783319906959 $q (electronic bk.)
020 $a 9783319906942 $q (paper)
024 7 $a 10.1007/978-3-319-90695-9 $2 doi
035 $a 978-3-319-90695-9
040 $a GP $c GP
041 0 $a eng
050 4 $a QH588.S83 $b S74 2018
072 7 $a PSAK $2 bicssc
072 7 $a SCI017000 $2 bisacsh
072 7 $a SCI049000 $2 bisacsh
082 0 4 $a 616.02774 $2 23
090 $a QH588.S83 $b S824 2018
245 0 0 $a Stem cell genetics for biomedical research $h [electronic resource] : $b past, present, and future / $c edited by Raul Delgado-Morales.
260 $a Cham : $c 2018. $b Springer International Publishing : $b Imprint: Springer,
300 $a xi, 426 p. : $b digital ; $c 24 cm.
505 0 $a Part I: Stem cells for brain disorders -- Chapter1: Human induced pluripotent stem cell-derived neurons to model and gain insights into Alzheimer's disease pathogenesis -- Chapter2: Modeling schizophrenia with human stem cells -- Chapter3: Rett Syndrome and Stem Cell research -- Chapter4: Stem Cell Applications in Spinal Cord Injury: A Primer -- Chapter5: Cell-Based Therapy for Retinal Degenerative Disease -- Chapter6: Past, present and future of cell based-therapy in progressive multiple sclerosis -- Part II: Stem cells for cardiovascular diseases -- Chapter7: Cardiac Stem Cells: a plethora of potential therapies for myocardial regeneration within reach -- Chapter8: Human Induced Pluripotent Stem Cell-derived Cardiomyocytes in the Evaluation of Cardiotoxic Potential of Drugs -- Part III: Stem cells for general medicine -- Chapter9: Regenerative medicine for diabetes treatment: new β-cell sources -- Chapter10: Dental pulp stem cells promote wound healing and muscle regeneration -- Chapter11: From bench to bedside of mesenchymal Stem Cells use for Rheumatoid Arthritis treatment -- Chapter12: Stem Cells and Cancer -- Chapter13: The relevance of induced pluripotent stem cells for the study of physiological and premature aging -- Part IV: Technical challenges and future -- Chapter14: Pluripotent stem cell banks -- Chapter15: Genetic and Epigenetic engineering: the CRISPR/Cas9 era.
520 $a This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer's disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.
650 0 $a Stem cells $x Research. $3 674469
650 0 $a Human genetics. $3 596505
650 0 $a Medicine $x Research. $3 592977
650 1 4 $a Life Sciences. $3 593888
650 2 4 $a Stem Cells. $3 782732
650 2 4 $a Human Genetics. $3 593893
650 2 4 $a Molecular Medicine. $3 668353
700 1 $a Delgado-Morales, Raul. $3 1142094
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-90695-9
950 $a Biomedical and Life Sciences (Springer-11642)