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Targeting protein-protein interactio...

Sheng, Chunquan.

Targeting protein-protein interactions by small molecules

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Targeting protein-protein interactions by small molecules/ edited by Chunquan Sheng, Gunda I. Georg.
其他作者:	Sheng, Chunquan.
出版者:	Singapore :Springer Singapore : : 2018.,
面頁冊數:	xi, 329 p. :digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Protein-protein interactions. -
電子資源:	http://dx.doi.org/10.1007/978-981-13-0773-7
ISBN:	9789811307737

Targeting protein-protein interactions by small molecules
Targeting protein-protein interactions by small molecules[electronic resource] /edited by Chunquan Sheng, Gunda I. Georg. - Singapore :Springer Singapore :2018. - xi, 329 p. :digital ;24 cm.

This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.

ISBN: 9789811307737

Standard No.: 10.1007/978-981-13-0773-7doiSubjects--Topical Terms:

668549
Protein-protein interactions.

LC Class. No.: QP551.5 / .T374 2018

Dewey Class. No.: 572.64

Targeting protein-protein interactions by small molecules
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245 0 0 $a Targeting protein-protein interactions by small molecules $h [electronic resource] / $c edited by Chunquan Sheng, Gunda I. Georg.
260 $a Singapore : $c 2018. $b Springer Singapore : $b Imprint: Springer,
300 $a xi, 329 p. : $b digital ; $c 24 cm.
520 $a This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.
650 0 $a Protein-protein interactions. $3 668549
650 0 $a Molecular association. $3 677045
650 0 $a Biochemistry. $3 582831
650 1 4 $a Chemistry. $3 593913
650 2 4 $a Medicinal Chemistry. $3 668872
650 2 4 $a Pharmaceutical Sciences/Technology. $3 768561
650 2 4 $a Bioorganic Chemistry. $3 677511
650 2 4 $a Protein Science. $3 782127
700 1 $a Sheng, Chunquan. $3 1205876
700 1 $a Georg, Gunda I. $3 1205877
710 2 $a SpringerLink (Online service) $3 593884
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856 4 0 $u http://dx.doi.org/10.1007/978-981-13-0773-7
950 $a Chemistry and Materials Science (Springer-11644)

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