國立虎尾科技大學 |

Nuclear-cytoplasmic transport

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Nuclear-cytoplasmic transport/ edited by Weidong Yang.
other author:	Yang, Weidong.
Published:	Cham :Springer International Publishing : : 2018.,
Description:	vi, 274 p. :digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Cytoplasm. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-77309-4
ISBN:	9783319773094

Nuclear-cytoplasmic transport
Nuclear-cytoplasmic transport[electronic resource] /edited by Weidong Yang. - Cham :Springer International Publishing :2018. - vi, 274 p. :digital ;24 cm. - Nucleic acids and molecular biology,v.330933-1891 ;. - Nucleic acids and molecular biology ;27..

Assembly of the nuclear pore complex -- Structure of Yeast nuclear pore complexes -- Structure and function of nucleoporins in nuclear transport -- Dynamic structures of the nuclear pore complex and their roles in nucleo-cytoplasmic transport -- Non-canonical roles of nuclear pore proteins -- On the role of the channel nucleoporins in nuclear transport -- Structures of Importins and Exportins -- Navigating the Nuclear Envelope: one or multiple transport mechanisms for integral membrane proteins? -- mRNA export and its dysregulation in disease -- Coarse-grained molecular dynamics of the natively-unfolded domain of the NPC -- On the effects of leukemogenic nucleoporin fusion proteins on nucleocytoplasmic transport and gene expression -- Structure and Function of the Nuclear Pore Complex Revealed by Advanced Fluorescence Microscopy.

Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.

ISBN: 9783319773094

Standard No.: 10.1007/978-3-319-77309-4doiSubjects--Topical Terms:

1206916
Cytoplasm.

LC Class. No.: QH591 / .N835 2018

Dewey Class. No.: 571.65

Nuclear-cytoplasmic transport
LDR:02586nam a2200325 a 4500 001 927538
003 DE-He213
005 20190122094556.0
006 m d
007 cr nn 008maaau
008 190626s2018 gw s 0 eng d
020 $a 9783319773094 $q (electronic bk.)
020 $a 9783319773087 $q (paper)
024 7 $a 10.1007/978-3-319-77309-4 $2 doi
035 $a 978-3-319-77309-4
040 $a GP $c GP
041 0 $a eng
050 4 $a QH591 $b .N835 2018
072 7 $a PSB $2 bicssc
072 7 $a SCI007000 $2 bisacsh
082 0 4 $a 571.65 $2 23
090 $a QH591 $b .N964 2018
245 0 0 $a Nuclear-cytoplasmic transport $h [electronic resource] / $c edited by Weidong Yang.
260 $a Cham : $c 2018. $b Springer International Publishing : $b Imprint: Springer,
300 $a vi, 274 p. : $b digital ; $c 24 cm.
490 1 $a Nucleic acids and molecular biology, $x 0933-1891 ; $v v.33
505 0 $a Assembly of the nuclear pore complex -- Structure of Yeast nuclear pore complexes -- Structure and function of nucleoporins in nuclear transport -- Dynamic structures of the nuclear pore complex and their roles in nucleo-cytoplasmic transport -- Non-canonical roles of nuclear pore proteins -- On the role of the channel nucleoporins in nuclear transport -- Structures of Importins and Exportins -- Navigating the Nuclear Envelope: one or multiple transport mechanisms for integral membrane proteins? -- mRNA export and its dysregulation in disease -- Coarse-grained molecular dynamics of the natively-unfolded domain of the NPC -- On the effects of leukemogenic nucleoporin fusion proteins on nucleocytoplasmic transport and gene expression -- Structure and Function of the Nuclear Pore Complex Revealed by Advanced Fluorescence Microscopy.
520 $a Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.
650 0 $a Cytoplasm. $3 1206916
650 0 $a Nucleoproteins. $3 1205733
650 1 4 $a Life Sciences. $3 593888
650 2 4 $a Nucleic Acid Chemistry. $3 716485
650 2 4 $a Applied Microbiology. $3 673403
650 2 4 $a Eukaryotic Microbiology. $3 676937
650 2 4 $a Evolutionary Biology. $3 668573
700 1 $a Yang, Weidong. $3 1206915
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Nucleic acids and molecular biology ; $v 27. $3 884428
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-77309-4
950 $a Biomedical and Life Sciences (Springer-11642)