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Complement activation in malaria immunity and pathogenesis

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Complement activation in malaria immunity and pathogenesis/ edited by Jose A. Stoute.
other author:	Stoute, Jose A.
Published:	Cham :Springer International Publishing : : 2018.,
Description:	xii, 149 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Complement activation. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-77258-5
ISBN:	9783319772585

Complement activation in malaria immunity and pathogenesis
Complement activation in malaria immunity and pathogenesis[electronic resource] /edited by Jose A. Stoute. - Cham :Springer International Publishing :2018. - xii, 149 p. :ill., digital ;24 cm.

The Complement System -- Mechanisms of Complement Activation in Malaria -- Role of Complement in Severe Malarial Anemia -- Role of Complement in Cerebral Malaria -- Role of Complement in Placental Malaria -- Complement Evasion Mechanisms of the Human Pathogen Plasmodium falciparum -- Role of Complement in Immunity Against Malaria -- Complement-like System in the Mosquito Responses Against Malaria Parasites.

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.

ISBN: 9783319772585

Standard No.: 10.1007/978-3-319-77258-5doiSubjects--Topical Terms:

1206931
Complement activation.

LC Class. No.: RC157 / .C667 2018

Dewey Class. No.: 616.9362

Complement activation in malaria immunity and pathogenesis
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245 0 0 $a Complement activation in malaria immunity and pathogenesis $h [electronic resource] / $c edited by Jose A. Stoute.
260 $a Cham : $c 2018. $b Springer International Publishing : $b Imprint: Springer,
300 $a xii, 149 p. : $b ill., digital ; $c 24 cm.
505 0 $a The Complement System -- Mechanisms of Complement Activation in Malaria -- Role of Complement in Severe Malarial Anemia -- Role of Complement in Cerebral Malaria -- Role of Complement in Placental Malaria -- Complement Evasion Mechanisms of the Human Pathogen Plasmodium falciparum -- Role of Complement in Immunity Against Malaria -- Complement-like System in the Mosquito Responses Against Malaria Parasites.
520 $a Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.
650 0 $a Complement activation. $3 1206931
650 0 $a Immunity. $3 581467
650 0 $a Malaria $x Pathogenesis. $3 1206932
650 0 $a Malaria $x Immunological aspects. $3 669071
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Immunology. $3 592892
650 2 4 $a Parasitology. $3 669054
650 2 4 $a Infectious Diseases. $3 668393
650 2 4 $a Tropical Medicine. $3 668883
650 2 4 $a Laboratory Medicine. $3 673604
700 1 $a Stoute, Jose A. $3 1206930
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-77258-5
950 $a Biomedical and Life Sciences (Springer-11642)