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Escherichia coli, a versatile pathogen

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Escherichia coli, a versatile pathogen/ edited by Gad Frankel, Eliora Z Ron.
other author:	Frankel, Gad.
Published:	Cham :Springer International Publishing : : 2018.,
Description:	vii, 242 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Escherichia coli. -
Online resource:	https://doi.org/10.1007/978-3-319-99664-6
ISBN:	9783319996646

Escherichia coli, a versatile pathogen
Escherichia coli, a versatile pathogen[electronic resource] /edited by Gad Frankel, Eliora Z Ron. - Cham :Springer International Publishing :2018. - vii, 242 p. :ill. (some col.), digital ;24 cm. - Current topics in microbiology and immunology,v.4160070-217X ;. - Current topics in microbiology and immunology ;v.355..

Shigella and enteroinvasive Escherichia coli -- Enteroaggregative Escherichia coli -- The Type III Secretion System of pathogenic Escherichia coli -- Modulation of host cell processes by T3SS effectors -- The 2011 German enterohemorrhagic Escherichia coli O104:H4 outbreak - the danger is still out there -- Extraintestinal Pathogenic Escherichia coli -- Pandemic bacteremic Escherichia coli strains: evolution and emergence of drug resistant pathogens -- Current Trends in Antimicrobial Resistance of Escherichia coli -- Vaccines against Escherichia coli.

Escherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection. This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development.

ISBN: 9783319996646

Standard No.: 10.1007/978-3-319-99664-6doiSubjects--Topical Terms:

895584
Escherichia coli.

LC Class. No.: QR201.E82 / E834 2018

Dewey Class. No.: 579.342

Escherichia coli, a versatile pathogen
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520 $a Escherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection. This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development.
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