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Chiral photochemical scissors target...
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Buranaprapuk, Apinya,
Chiral photochemical scissors targeting proteins /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Chiral photochemical scissors targeting proteins // Challa Vijaya Kumar, Apinya Buranaprapuk.
作者:
Kumar, Challa V.
其他作者:
Buranaprapuk, Apinya,
出版者:
Hackensack, New Jersey :World Scientific, : c2019.,
面頁冊數:
xvii, 428 p. :ill. (some col.) ; : 24 cm.;
標題:
Photochemistry. -
ISBN:
9789813237612 (cloth) :
Chiral photochemical scissors targeting proteins /
Kumar, Challa V.
Chiral photochemical scissors targeting proteins /
Challa Vijaya Kumar, Apinya Buranaprapuk. - Hackensack, New Jersey :World Scientific,c2019. - xvii, 428 p. :ill. (some col.) ;24 cm.
Includes bibliographical references and index.
Introduction -- Photophysical processes -- Protein structure -- Protein-ligand interactions -- Binding thermodynamics -- Photochemical protein scissors -- Molecular architecture of protein photocleavage reagents -- Photochemical scissors for BSA -- Chiral recognition -- Tuning the linker of the photoreagent -- Protein scissors targeting lysozyme -- Targeting biotin-binding sites on avidin with py-biotin -- Inorganic photochemical proteases: Co(III)polyamine -- Photocleavage of pepsin by Mo(VI) complexes -- Photocleavage by uranyl ion -- Computational modeling and docking studies -- General methods for studying protein-ligand interaction and protein cleavage.
"The remarkable ability to target one or even a couple of sites on a large protein with a small molecule, under photochemical control, is a considerable challenge and this challenge has been addressed in some depth in this book. Systematic modification of the structure of the photoreagent provided valuable information on the binding site recognition as well as the mechanism of the photocleavage reaction"--
ISBN: 9789813237612 (cloth) :NT4524
LCCN: 2018039240Subjects--Topical Terms:
583650
Photochemistry.
LC Class. No.: QD601.3 / .K86 2019
Dewey Class. No.: 541/.35
Chiral photochemical scissors targeting proteins /
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Introduction -- Photophysical processes -- Protein structure -- Protein-ligand interactions -- Binding thermodynamics -- Photochemical protein scissors -- Molecular architecture of protein photocleavage reagents -- Photochemical scissors for BSA -- Chiral recognition -- Tuning the linker of the photoreagent -- Protein scissors targeting lysozyme -- Targeting biotin-binding sites on avidin with py-biotin -- Inorganic photochemical proteases: Co(III)polyamine -- Photocleavage of pepsin by Mo(VI) complexes -- Photocleavage by uranyl ion -- Computational modeling and docking studies -- General methods for studying protein-ligand interaction and protein cleavage.
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"The remarkable ability to target one or even a couple of sites on a large protein with a small molecule, under photochemical control, is a considerable challenge and this challenge has been addressed in some depth in this book. Systematic modification of the structure of the photoreagent provided valuable information on the binding site recognition as well as the mechanism of the photocleavage reaction"--
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