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Ex vivo engineering of the tumor mic...
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Ex vivo engineering of the tumor microenvironment
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Ex vivo engineering of the tumor microenvironment/ edited by Amir R. Aref, David Barbie.
other author:
Aref, Amir R.
Published:
Cham :Springer International Publishing : : 2017.,
Description:
ix, 135 p. :ill., digital ; : 24 cm.;
Contained By:
Springer eBooks
Subject:
Cancer - Molecular aspects. -
Online resource:
http://dx.doi.org/10.1007/978-3-319-45397-2
ISBN:
9783319453972
Ex vivo engineering of the tumor microenvironment
Ex vivo engineering of the tumor microenvironment
[electronic resource] /edited by Amir R. Aref, David Barbie. - Cham :Springer International Publishing :2017. - ix, 135 p. :ill., digital ;24 cm. - Cancer drug discovery and development,2196-9906. - Cancer drug discovery and development..
1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy.
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
ISBN: 9783319453972
Standard No.: 10.1007/978-3-319-45397-2doiSubjects--Topical Terms:
668357
Cancer
--Molecular aspects.
LC Class. No.: RC268.4
Dewey Class. No.: 616.994
Ex vivo engineering of the tumor microenvironment
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1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy.
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This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
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Medicine (Springer-11650)
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