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Metabolomics = from fundamentals to clinical applications /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Metabolomics/ edited by Alessandra Sussulini.
Reminder of title:	from fundamentals to clinical applications /
other author:	Sussulini, Alessandra.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	x, 350 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Systems biology. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-47656-8
ISBN:	9783319476568

Metabolomics = from fundamentals to clinical applications /
Metabolomicsfrom fundamentals to clinical applications /[electronic resource] :edited by Alessandra Sussulini. - Cham :Springer International Publishing :2017. - x, 350 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,9650065-2598 ;. - Advances in experimental medicine and biology ;780..

Part I: Fundamentals and analytical methodologies in metabolomics -- 1. Metabolomics: definitions and significance in systems biology -- 2. Collection and preparation of clinical samples for metabolomics -- 3. NMR strategies in metabolomics -- 5. Strategies involving MS combined with chromatography in metabolomics -- 6.MS combined with capillary electrophoresis in metabolomics -- Part II: Statistical analysis and data interpretation -- 7. Data pretreatment: How to prepare a metabolomics dataset for statistical analysis? -- 8. Chemometrics in metabolomics -- Understanding metabolomics data: Metabolite identification and biological relevance -- Part III: Applications and future trends of metabolomics in clinical cases -- 9. Applications of metabolomics in cancer studies -- 10. Chronic diseases and lifestyle biomarkers identification by metabolomics -- 11. Metabolomics in neurological and psychiatric diseases -- 12. Metabolite profiling by MS imaging -- 13. Single cell metabolomics.

This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.

ISBN: 9783319476568

Standard No.: 10.1007/978-3-319-47656-8doiSubjects--Topical Terms:

600045
Systems biology.

LC Class. No.: QH324.2

Dewey Class. No.: 570.285

Metabolomics = from fundamentals to clinical applications /
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