國立虎尾科技大學 |

The actin cytoskeleton and bacterial infection

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The actin cytoskeleton and bacterial infection/ edited by Hans Georg Mannherz.
other author:	Mannherz, Hans Georg.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	x, 242 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Actin. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-50047-8
ISBN:	9783319500478

The actin cytoskeleton and bacterial infection
The actin cytoskeleton and bacterial infection[electronic resource] /edited by Hans Georg Mannherz. - Cham :Springer International Publishing :2017. - x, 242 p. :ill., digital ;24 cm. - Current topics in microbiology and immunology,v.3990070-217X ;. - Current topics in microbiology and immunology ;v.355..

Actin structure and dynamics -- Influence of binary actin-depolymerizing toxins on the microtubule system -- ADP-ribosylation of actin by Photorhabdus luminescens TccC3 inhibits interaction with actin binding proteins essential for treadmilling -- Pathogenic mechanisms of actin cross-linking toxins - peeling away the layers -- New concepts on bacterial effectors targeting Rho GTPases -- Interaction of bacterial ADPribosyltransferases with actin -- Yersinia's ways to activate and inactivate actin rearrangements in host cells -- The role of formins in phagocytosis of Borrelia by macrophages.

This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton. In short, this volume provides an overview of the various tricks bacteria have evolved to "act on actin" in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.

ISBN: 9783319500478

Standard No.: 10.1007/978-3-319-50047-8doiSubjects--Topical Terms:

782749
Actin.

LC Class. No.: QP552.A27

Dewey Class. No.: 572.66

The actin cytoskeleton and bacterial infection
LDR:02502nam a2200325 a 4500 001 958689
003 DE-He213
005 20170207130642.0
006 m d
007 cr nn 008maaau
008 201118s2017 gw s 0 eng d
020 $a 9783319500478 $q (electronic bk.)
020 $a 9783319500461 $q (paper)
024 7 $a 10.1007/978-3-319-50047-8 $2 doi
035 $a 978-3-319-50047-8
040 $a GP $c GP
041 0 $a eng
050 4 $a QP552.A27
072 7 $a MMFM $2 bicssc
072 7 $a MED052000 $2 bisacsh
082 0 4 $a 572.66 $2 23
090 $a QP552.A27 $b A188 2017
245 0 4 $a The actin cytoskeleton and bacterial infection $h [electronic resource] / $c edited by Hans Georg Mannherz.
260 $a Cham : $c 2017. $b Springer International Publishing : $b Imprint: Springer,
300 $a x, 242 p. : $b ill., digital ; $c 24 cm.
490 1 $a Current topics in microbiology and immunology, $x 0070-217X ; $v v.399
505 0 $a Actin structure and dynamics -- Influence of binary actin-depolymerizing toxins on the microtubule system -- ADP-ribosylation of actin by Photorhabdus luminescens TccC3 inhibits interaction with actin binding proteins essential for treadmilling -- Pathogenic mechanisms of actin cross-linking toxins - peeling away the layers -- New concepts on bacterial effectors targeting Rho GTPases -- Interaction of bacterial ADPribosyltransferases with actin -- Yersinia's ways to activate and inactivate actin rearrangements in host cells -- The role of formins in phagocytosis of Borrelia by macrophages.
520 $a This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton. In short, this volume provides an overview of the various tricks bacteria have evolved to "act on actin" in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.
650 0 $a Actin. $3 782749
650 0 $a Cytoskeleton. $3 686422
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Medical Microbiology. $3 668401
650 2 4 $a Pharmacology/Toxicology. $3 593882
700 1 $a Mannherz, Hans Georg. $3 1251030
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Current topics in microbiology and immunology ; $v v.355. $3 882363
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-50047-8
950 $a Biomedical and Life Sciences (Springer-11642)