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Free fatty acid receptors

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Free fatty acid receptors/ edited by Graeme Milligan, Ikuo Kimura.
其他作者:	Milligan, Graeme.
出版者:	Cham :Springer International Publishing : : 2017.,
面頁冊數:	viii, 256 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Fatty acids - Receptors. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-50693-7
ISBN:	9783319506937

Free fatty acid receptors
Free fatty acid receptors[electronic resource] /edited by Graeme Milligan, Ikuo Kimura. - Cham :Springer International Publishing :2017. - viii, 256 p. :ill., digital ;24 cm. - Handbook of experimental pharmacology,v.2360171-2004 ;. - Handbook of experimental pharmacology ;v.212..

Ligands at Free Fatty Acid Receptor 1 (GPR40) -- Ligands at Free Fatty Acid Receptor 2/3 (GPR43)/GPR41 -- Ligands at GPR84 -- Ligands at Free Fatty Acid Receptor 4 (GPR120) -- Homology modelling of FFA receptors -- Sensors for FFA receptors -- Key questions for translation of FFA receptors from pharmacology to medicines -- Polymorphic variation in FFA receptors. Functions and consequences -- The role and future of FFA1 as a therapeutic target -- Gut hormone regulation and secretion via FFA1 and FFA4 -- The role of FFA2 and FFA3 in metabolic regulation -- Anti-inflammatory and insulin sensitizing effects of free fatty acid receptors -- Free Fatty Acid receptors and cancer.

This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.

ISBN: 9783319506937

Standard No.: 10.1007/978-3-319-50693-7doiSubjects--Topical Terms:

1251041
Fatty acids
--Receptors.

LC Class. No.: QP752.F35

Dewey Class. No.: 572.57

Free fatty acid receptors
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