國立虎尾科技大學 |

Biliary disease = from science to clinic /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Biliary disease/ edited by Gideon Hirschfield, David Adams, Evaggelia Liaskou.
Reminder of title:	from science to clinic /
other author:	Hirschfield, Gideon.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	viii, 264 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Biliary tract - Diseases. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-50168-0
ISBN:	9783319501680

Biliary disease = from science to clinic /
Biliary diseasefrom science to clinic /[electronic resource] :edited by Gideon Hirschfield, David Adams, Evaggelia Liaskou. - Cham :Springer International Publishing :2017. - viii, 264 p. :ill., digital ;24 cm.

The clinical burden of biliary disease- a global perspective -- The healthy biliary tree- cellular and immunobiology -- Bile acid signalling and the current understanding of cholestasis: new opportunities for treatments? -- Animal models of biliary disease- current approaches and limitations -- The microbiome and human disease- a new organ of interest in biliary disease? -- Progressive familial intrahepatic cholestatic syndromes- genetic insights into biliary transporter function -- Biliary atresia- from pathology to treatment -- Drug induced cholestasis: mechanisms and importance -- Primary biliary cirrhosis- it's science and practice -- Primary sclerosing cholangitis- current concepts in biology and strategies for new therapy -- Cholangiocarcinoma- evaluation of risk and new treatment paradigms -- Gallstone disease in the 21st century: practice and controversies -- Autoimmune sclerosing cholangitis/IgG4 cholangiopathy- new diseases? -- Conclusions and future opportunities.

This book addresses the current understanding of the diagnosis and management of biliary disease across all ages, with emphasis on how the latest advances in clinical science may be integrated into current and future therapies. The coverage is wide ranging, encompassing congenital and acquired conditions including cholestatic syndromes, biliary atresia, drug-induced cholestasis, primary biliary cholangitis/cirrhosis, primary sclerosing cholangitis, cholangiocarcinoma, gallstone disease, and autoimmune sclerosing cholangitis. With contributions from basic and clinical scientists, the relevance of state-of-the-art mechanistic biology to diagnosis, treatment, and future opportunities for drug design is clearly explained. The balance between science and clinical practice will ensure that this book makes a lasting contribution to the field. A broad readership will find the book easy to access and a rich source of information on current best practice and evolving management strategies.

ISBN: 9783319501680

Standard No.: 10.1007/978-3-319-50168-0doiSubjects--Topical Terms:

683690
Biliary tract
--Diseases.

LC Class. No.: RC845

Dewey Class. No.: 616.36

Biliary disease = from science to clinic /
LDR:02927nam a2200313 a 4500 001 959175
003 DE-He213
005 20170830095926.0
006 m d
007 cr nn 008maaau
008 201118s2017 gw s 0 eng d
020 $a 9783319501680 $q (electronic bk.)
020 $a 9783319501666 $q (paper)
024 7 $a 10.1007/978-3-319-50168-0 $2 doi
035 $a 978-3-319-50168-0
040 $a GP $c GP
041 0 $a eng
050 4 $a RC845
072 7 $a MJH $2 bicssc
072 7 $a MED031000 $2 bisacsh
082 0 4 $a 616.36 $2 23
090 $a RC845 $b .B595 2017
245 0 0 $a Biliary disease $h [electronic resource] : $b from science to clinic / $c edited by Gideon Hirschfield, David Adams, Evaggelia Liaskou.
260 $a Cham : $c 2017. $b Springer International Publishing : $b Imprint: Springer,
300 $a viii, 264 p. : $b ill., digital ; $c 24 cm.
505 0 $a The clinical burden of biliary disease- a global perspective -- The healthy biliary tree- cellular and immunobiology -- Bile acid signalling and the current understanding of cholestasis: new opportunities for treatments? -- Animal models of biliary disease- current approaches and limitations -- The microbiome and human disease- a new organ of interest in biliary disease? -- Progressive familial intrahepatic cholestatic syndromes- genetic insights into biliary transporter function -- Biliary atresia- from pathology to treatment -- Drug induced cholestasis: mechanisms and importance -- Primary biliary cirrhosis- it's science and practice -- Primary sclerosing cholangitis- current concepts in biology and strategies for new therapy -- Cholangiocarcinoma- evaluation of risk and new treatment paradigms -- Gallstone disease in the 21st century: practice and controversies -- Autoimmune sclerosing cholangitis/IgG4 cholangiopathy- new diseases? -- Conclusions and future opportunities.
520 $a This book addresses the current understanding of the diagnosis and management of biliary disease across all ages, with emphasis on how the latest advances in clinical science may be integrated into current and future therapies. The coverage is wide ranging, encompassing congenital and acquired conditions including cholestatic syndromes, biliary atresia, drug-induced cholestasis, primary biliary cholangitis/cirrhosis, primary sclerosing cholangitis, cholangiocarcinoma, gallstone disease, and autoimmune sclerosing cholangitis. With contributions from basic and clinical scientists, the relevance of state-of-the-art mechanistic biology to diagnosis, treatment, and future opportunities for drug design is clearly explained. The balance between science and clinical practice will ensure that this book makes a lasting contribution to the field. A broad readership will find the book easy to access and a rich source of information on current best practice and evolving management strategies.
650 0 $a Biliary tract $x Diseases. $3 683690
650 1 4 $a Medicine & Public Health. $3 593949
650 2 4 $a Gastroenterology. $3 673684
650 2 4 $a Hepatology. $3 673859
650 2 4 $a Pediatrics. $3 644839
650 2 4 $a Nursing. $3 563081
650 2 4 $a Pathology. $3 668553
650 2 4 $a Imaging / Radiology. $3 669876
700 1 $a Hirschfield, Gideon. $3 1251723
700 1 $a Adams, David. $3 1251724
700 1 $a Liaskou, Evaggelia. $3 1251725
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-50168-0
950 $a Medicine (Springer-11650)