國立虎尾科技大學 |

Pain Control

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Pain Control/ edited by Hans-Georg Schaible.
其他作者:	Schaible, Hans-Georg.
面頁冊數:	VIII, 309 p. 31 illus., 22 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Pharmacology. -
電子資源:	https://doi.org/10.1007/978-3-662-46450-2
ISBN:	9783662464502

Pain Control
Pain Control[electronic resource] /edited by Hans-Georg Schaible. - 1st ed. 2015. - VIII, 309 p. 31 illus., 22 illus. in color.online resource. - Handbook of Experimental Pharmacology,2270171-2004 ;. - Handbook of Experimental Pharmacology,224.

Emerging concepts of pain therapy based on neuronal mechanisms -- The pharmacology of nociceptor priming -- Sodium channels and pain -- Role of nerve growth factor in pain -- Central sensitization in humans – assessment and pharmacology -- The role of NO in the spinal cord -- The role of the endocannabinoid system in pain -- The role of glia in the spinal cord in neuropathic and inflammatory pain -- Plasticity of inhibition in the spinal cord -- Gene regulation in nociception. Modulation of peripheral inflammation by the spinal cord -- The relationship between opioids and cytokines in the spinal cord -- The role of proteases in pain. Pain-related pharmacology in the amygdala -- Pain and itch – differences and commonalities.

This volume addresses neuronal pain mechanisms at the peripheral, spinal and supraspinal level which are thought to significantly contribute to pain and which may be the basis for the development of new treatment principles. Chapters on nociceptive mechanisms in the peripheral nociceptive system address the concept of hyperalgesic priming, the role of voltage-gated sodium channels in different inflammatory and neuropathic pain states, the hyperalgesic effects of NGF in different tissues and in inflammatory and neuropathic pain states, and the contribution of proteinase activated receptors (PAR) to the development of pain in several chronic pain conditions. Chapters on nociceptive mechanisms in the spinal cord address the particular role of NO and of glial cell activation in the generation and maintenance of inflammatory and neuropathic pain and it discusses the potential role of local inhibitory interneurons, of the endogenous endocannabinoid system and the importance of non-neuronal immune mechanisms in opioid signaling in the control of pain. Furthermore, it is presented how spinal mechanisms contribute to the expression of peripheral inflammation.

ISBN: 9783662464502

Standard No.: 10.1007/978-3-662-46450-2doiSubjects--Topical Terms:

583819
Pharmacology.

LC Class. No.: RM1-950

Dewey Class. No.: 615

Pain Control
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