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The Future of HIV-1 Therapeutics = Resistance Is Futile? /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	The Future of HIV-1 Therapeutics/ edited by Bruce E. Torbett, David S. Goodsell, Douglas D. Richman.
其他題名:	Resistance Is Futile? /
其他作者:	Torbett, Bruce E.
面頁冊數:	X, 254 p.online resource. :
Contained By:	Springer Nature eBook
標題:	Drug resistance. -
電子資源:	https://doi.org/10.1007/978-3-319-18518-7
ISBN:	9783319185187

The Future of HIV-1 Therapeutics = Resistance Is Futile? /
The Future of HIV-1 TherapeuticsResistance Is Futile? /[electronic resource] :edited by Bruce E. Torbett, David S. Goodsell, Douglas D. Richman. - 1st ed. 2015. - X, 254 p.online resource. - Current Topics in Microbiology and Immunology,3890070-217X ;. - Current Topics in Microbiology and Immunology,387.

HIV Therapy Looking Towards the Future -- Computational challenges of structure-based approaches applied to HIV -- Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1 -- HIV-1 integrase multimerization as a therapeutic target -- Targeting HIV transcription: The quest for a functional cure -- Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder -- HIV-1 Gag: An Emerging Target for Antiretroviral Therapy -- The Triple Threat of HIV-1 Protease Inhibitors -- Illustrations of the HIV Life Cycle.

This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.

ISBN: 9783319185187

Standard No.: 10.1007/978-3-319-18518-7doiSubjects--Topical Terms:

872072
Drug resistance.

LC Class. No.: QR177

Dewey Class. No.: 616.9041

The Future of HIV-1 Therapeutics = Resistance Is Futile? /
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