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Textbook of Cell Signalling in Cancer = An Educational Approach /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Textbook of Cell Signalling in Cancer/ by Jacques Robert.
Reminder of title:	An Educational Approach /
Author:	Robert, Jacques.
Description:	XXIII, 328 p. 126 illus., 122 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Oncology . -
Online resource:	https://doi.org/10.1007/978-3-319-14340-8
ISBN:	9783319143408

Textbook of Cell Signalling in Cancer = An Educational Approach /
Robert, Jacques.

Textbook of Cell Signalling in CancerAn Educational Approach /[electronic resource] :by Jacques Robert. - 1st ed. 2015. - XXIII, 328 p. 126 illus., 122 illus. in color.online resource.

Growth Factors and Tyrosine Kinase Receptors -- MAP Kinases Pathway -- Phosphatidylinositol 3-Kinase Pathway -- Cytokine Pathway -- TGFβ Pathway -- G-proteins–coupled Receptors -- Wnt Pathway -- Notch Pathway -- Hedgehog Pathway -- Integrins -- Semaphorins and Adhesion Molecules -- Toll-like Receptors, Interleukin 1 (IL1) and NFκB -- Lymphocyte Receptors Pathways -- Nuclear Receptors Pathways -- Ion Channels–coupled Receptors -- Signalling by Oxygen and Nitric Oxide -- Cell Cycle Control -- Apoptosis Induction and Regulation.

This book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis. This comprehensive reference text is based on the master’s courses delivered by Prof. Jacques Robert to graduate students at the University of Bordeaux, France. It includes a large number of colour schemas and figures that have been improved year after year for educational purposes. Signalling pathways are described individually and in depth, but without ignoring the multiplicity of interconnections and crosstalk. The presentation of each pathway is followed by a brief description of the alterations found in cancers as well as of the targeted pharmacological approaches that can be used to prevent or overcome the consequences of these oncogenic alterations. The basic mechanisms of molecular biology at the DNA replication, RNA transcription and protein activity levels are presented in a series of didactic annexes, enabling readers to better understand the alterations in signalling pathways.

ISBN: 9783319143408

Standard No.: 10.1007/978-3-319-14340-8doiSubjects--Topical Terms:

1253469
Oncology .

LC Class. No.: RC254-282

Dewey Class. No.: 616.994

Textbook of Cell Signalling in Cancer = An Educational Approach /
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