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Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems/ by Monica Frega.
作者:	Frega, Monica.
面頁冊數:	XIII, 148 p. 97 illus., 43 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Biomedical engineering. -
電子資源:	https://doi.org/10.1007/978-3-319-30237-9
ISBN:	9783319302379

Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems
Frega, Monica.

Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems[electronic resource] /by Monica Frega. - 1st ed. 2016. - XIII, 148 p. 97 illus., 43 illus. in color.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.

Introduction -- Dissociated Neuronal Networks Coupled to Micro-Electrode Arrays Devices -- In Vitro Neuronal Networks -- 3D Neuronal Networks: State of the Art -- 3D Neuronal Networks Coupled to MEAs -- Neuro-pharmacological Studies -- Discussion and Conclusion -- Data Analysis.

The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, differs between the two models, with the 3D system being better able to emulate the in vivo behaviour of neural networks. The book offers an extensive analysis of the system, from the theoretical background, to its design and applications in neuro-pharmacological studies. Moreover, it includes a concise yet comprehensive introduction to both 2D and 3D neuronal networks coupled to MEAs, and discusses the advantages, limitations and challenges of their applications as cellular and tissue-like in vitro experimental model systems. < .

ISBN: 9783319302379

Standard No.: 10.1007/978-3-319-30237-9doiSubjects--Topical Terms:

588770
Biomedical engineering.

LC Class. No.: R856-857

Dewey Class. No.: 610.28

Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems
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