國立虎尾科技大學 |

Pancreatic Islet Isolation = From the Mouse to the Clinic /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Pancreatic Islet Isolation/ edited by Miriam Ramírez-Domínguez.
Reminder of title:	From the Mouse to the Clinic /
other author:	Ramírez-Domínguez, Miriam.
Description:	XII, 123 p. 31 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Cell biology. -
Online resource:	https://doi.org/10.1007/978-3-319-39824-2
ISBN:	9783319398242

Pancreatic Islet Isolation = From the Mouse to the Clinic /
Pancreatic Islet IsolationFrom the Mouse to the Clinic /[electronic resource] :edited by Miriam Ramírez-Domínguez. - 1st ed. 2016. - XII, 123 p. 31 illus. in color.online resource. - Advances in Experimental Medicine and Biology,9380065-2598 ;. - Advances in Experimental Medicine and Biology,889.

Historical Background of Pancreatic Islet Isolation, Miriam Ramírez-Domínguez -- The Different Faces of the Pancreatic Islets, Midhat H.Abdulreda, Rayner Rodriguez-Diaz, Over Cabrera, Alejandro Caicedo, Per-Olof Berggren -- Isolation of Mouse Pancreatic Islets of Langerhans, Miriam Ramírez-Domínguez -- Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets, Heide Brandhorst, Paul R.V. Johnson, Daniel Brandhorst -- Isolation of Pancreatic Islets from NonHuman Primates, Dora M. Berman -- Necessities for a Clinical Islet Program, Wayne John Hawthorne -- Clinical Islet Isolation, Wayne John Hawthorne, Lindy Jane Williams, Yi Vee Chew -- Index.

Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.

ISBN: 9783319398242

Standard No.: 10.1007/978-3-319-39824-2doiSubjects--Topical Terms:

1253486
Cell biology.

LC Class. No.: QH573-671

Dewey Class. No.: 571.6

Pancreatic Islet Isolation = From the Mouse to the Clinic /
LDR:03338nam a22004095i 4500 001 972193
003 DE-He213
005 20200707100430.0
007 cr nn 008mamaa
008 201211s2016 gw | s |||| 0|eng d
020 $a 9783319398242 $9 978-3-319-39824-2
024 7 $a 10.1007/978-3-319-39824-2 $2 doi
035 $a 978-3-319-39824-2
050 4 $a QH573-671
072 7 $a PSF $2 bicssc
072 7 $a SCI049000 $2 bisacsh
072 7 $a PSF $2 thema
082 0 4 $a 571.6 $2 23
245 1 0 $a Pancreatic Islet Isolation $h [electronic resource] : $b From the Mouse to the Clinic / $c edited by Miriam Ramírez-Domínguez.
250 $a 1st ed. 2016.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a XII, 123 p. 31 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Advances in Experimental Medicine and Biology, $x 0065-2598 ; $v 938
505 0 $a Historical Background of Pancreatic Islet Isolation, Miriam Ramírez-Domínguez -- The Different Faces of the Pancreatic Islets, Midhat H.Abdulreda, Rayner Rodriguez-Diaz, Over Cabrera, Alejandro Caicedo, Per-Olof Berggren -- Isolation of Mouse Pancreatic Islets of Langerhans, Miriam Ramírez-Domínguez -- Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets, Heide Brandhorst, Paul R.V. Johnson, Daniel Brandhorst -- Isolation of Pancreatic Islets from NonHuman Primates, Dora M. Berman -- Necessities for a Clinical Islet Program, Wayne John Hawthorne -- Clinical Islet Isolation, Wayne John Hawthorne, Lindy Jane Williams, Yi Vee Chew -- Index.
520 $a Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
650 0 $a Cell biology. $3 1253486
650 0 $a Biomedical engineering. $3 588770
650 0 $a Endocrinology . $3 1254221
650 0 $a Animal models in research. $3 581737
650 1 4 $a Cell Biology. $3 593889
650 2 4 $a Biomedical Engineering and Bioengineering. $3 1211019
650 2 4 $a Endocrinology. $3 645497
650 2 4 $a Animal Models. $3 784995
700 1 $a Ramírez-Domínguez, Miriam. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1267382
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319398228
776 0 8 $i Printed edition: $z 9783319398235
776 0 8 $i Printed edition: $z 9783319819747
830 0 $a Advances in Experimental Medicine and Biology, $x 0065-2598 ; $v 889 $3 1253792
856 4 0 $u https://doi.org/10.1007/978-3-319-39824-2
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)