國立虎尾科技大學 |

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification/ by Jianpeng Wang.
Author:	Wang, Jianpeng.
Description:	XIII, 96 p. 46 illus., 41 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Biotechnology. -
Online resource:	https://doi.org/10.1007/978-3-662-53399-4
ISBN:	9783662533994

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification
Wang, Jianpeng.

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification[electronic resource] /by Jianpeng Wang. - 1st ed. 2016. - XIII, 96 p. 46 illus., 41 illus. in color.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.

Introduction -- Biological Active Antifungal Peptides -- Protein Ligands Engineering -- Coiled Coil Binding Induced Covalent Cross-linking -- Cell Surface Receptor Labeling -- Summary and Conclusion.

This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.

ISBN: 9783662533994

Standard No.: 10.1007/978-3-662-53399-4doiSubjects--Topical Terms:

554955
Biotechnology.

LC Class. No.: TP248.13-248.65

Dewey Class. No.: 660.6

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification
LDR:02676nam a22004095i 4500 001 972998
003 DE-He213
005 20200704081819.0
007 cr nn 008mamaa
008 201211s2016 gw | s |||| 0|eng d
020 $a 9783662533994 $9 978-3-662-53399-4
024 7 $a 10.1007/978-3-662-53399-4 $2 doi
035 $a 978-3-662-53399-4
050 4 $a TP248.13-248.65
072 7 $a TCB $2 bicssc
072 7 $a SCI010000 $2 bisacsh
072 7 $a TCB $2 thema
082 0 4 $a 660.6 $2 23
100 1 $a Wang, Jianpeng. $4 aut $4 http://id.loc.gov/vocabulary/relators/aut $3 1113431
245 1 0 $a Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification $h [electronic resource] / $c by Jianpeng Wang.
250 $a 1st ed. 2016.
264 1 $a Berlin, Heidelberg : $b Springer Berlin Heidelberg : $b Imprint: Springer, $c 2016.
300 $a XIII, 96 p. 46 illus., 41 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Springer Theses, Recognizing Outstanding Ph.D. Research, $x 2190-5053
505 0 $a Introduction -- Biological Active Antifungal Peptides -- Protein Ligands Engineering -- Coiled Coil Binding Induced Covalent Cross-linking -- Cell Surface Receptor Labeling -- Summary and Conclusion.
520 $a This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.
650 0 $a Biotechnology. $3 554955
650 0 $a Proteins . $3 1253493
650 0 $a Nanotechnology. $3 557660
650 0 $a Bioorganic chemistry. $3 743635
650 2 4 $a Protein Science. $3 782127
650 2 4 $a Bioorganic Chemistry. $3 677511
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783662533970
776 0 8 $i Printed edition: $z 9783662533987
776 0 8 $i Printed edition: $z 9783662571347
830 0 $a Springer Theses, Recognizing Outstanding Ph.D. Research, $x 2190-5053 $3 1253569
856 4 0 $u https://doi.org/10.1007/978-3-662-53399-4
912 $a ZDB-2-CMS
912 $a ZDB-2-SXC
950 $a Chemistry and Materials Science (SpringerNature-11644)
950 $a Chemistry and Material Science (R0) (SpringerNature-43709)