國立虎尾科技大學 |

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification/ by Jianpeng Wang.
作者:	Wang, Jianpeng.
面頁冊數:	XIII, 96 p. 46 illus., 41 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Biotechnology. -
電子資源:	https://doi.org/10.1007/978-3-662-53399-4
ISBN:	9783662533994

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification
Wang, Jianpeng.

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification[electronic resource] /by Jianpeng Wang. - 1st ed. 2016. - XIII, 96 p. 46 illus., 41 illus. in color.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.

Introduction -- Biological Active Antifungal Peptides -- Protein Ligands Engineering -- Coiled Coil Binding Induced Covalent Cross-linking -- Cell Surface Receptor Labeling -- Summary and Conclusion.

This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.

ISBN: 9783662533994

Standard No.: 10.1007/978-3-662-53399-4doiSubjects--Topical Terms:

554955
Biotechnology.

LC Class. No.: TP248.13-248.65

Dewey Class. No.: 660.6

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification
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