國立虎尾科技大學 |

Circulating Tumor Cells

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Circulating Tumor Cells/ edited by Richard J. Cote, Ram Datar.
其他作者:	Cote, Richard J.
面頁冊數:	XXIV, 333 p. 31 illus., 29 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Cancer research. -
電子資源:	https://doi.org/10.1007/978-1-4939-3363-1
ISBN:	9781493933631

Circulating Tumor Cells
Circulating Tumor Cells[electronic resource] /edited by Richard J. Cote, Ram Datar. - 1st ed. 2016. - XXIV, 333 p. 31 illus., 29 illus. in color.online resource. - Current Cancer Research,2199-2584. - Current Cancer Research,.

Preface -- Foreword -- Section I. Technologies for CTC Identification -- 1. Significance of Studying Circulating Tumor Cells -- 2. Affinity-Based Enrichment of Circulating Tumor Cells -- 3. Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Characterization -- 4. Molecular Assays for the Detection and Molecular Characterization of CTCs -- 5. Cancer Stem Cells and Circulating Tumor Cells Molecular Markers, Isolation Techniques and Clinical Implications -- Section II. Fundamental Studies of CTC -- 6. Circulating Tumor Cells and Tumor Dormancy -- 7. Prevention of Conversion of Tumor Dormancy into Proliferative Metastases -- 8. Genesis of Circulating Tumor Cells through Epithelial-Mesenchymal Transition as a Mechanism for Distant Dissemination -- Section III. CTC Analysis -- 9. CTC Analysis FISH, ISH, Array-CGH and Other Molecular Assays -- 10. Genome-Wide Gene Copy Number Analysis of Circulating Tumor Cells -- 11. Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells -- 12. Prognostic Implications of CTC in Breast Cancer -- Section IV. Potential Clinical Applications of CTC -- 13. CTC in Advanced Breast Cancer Prognosis, Monitoring and Clinical Utility -- 14. Evolution of Metastatic Disease: The Need for Monitoring and Emerging Therapeutic Opportunities -- 15. CTC for Biomarker and Companion Diagnostic Development -- 16. Perspectives on Clinical Applications of CTCs -- Index.

This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers. CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive “liquid biopsy” procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development.There has been rapid progress in the field, fueled by research in basic science, biomedical engineering, and clinical applications. This book presents the latest developments from world-wide leaders, and will be useful for anyone interested in this important and expanding field.

ISBN: 9781493933631

Standard No.: 10.1007/978-1-4939-3363-1doiSubjects--Topical Terms:

1253664
Cancer research.

LC Class. No.: RC261-271

Dewey Class. No.: 614.5999

Circulating Tumor Cells
LDR:04018nam a22004095i 4500 001 978061
003 DE-He213
005 20200630072558.0
007 cr nn 008mamaa
008 201211s2016 xxu| s |||| 0|eng d
020 $a 9781493933631 $9 978-1-4939-3363-1
024 7 $a 10.1007/978-1-4939-3363-1 $2 doi
035 $a 978-1-4939-3363-1
050 4 $a RC261-271
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 614.5999 $2 23
245 1 0 $a Circulating Tumor Cells $h [electronic resource] / $c edited by Richard J. Cote, Ram Datar.
250 $a 1st ed. 2016.
264 1 $a New York, NY : $b Springer New York : $b Imprint: Springer, $c 2016.
300 $a XXIV, 333 p. 31 illus., 29 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Current Cancer Research, $x 2199-2584
505 0 $a Preface -- Foreword -- Section I. Technologies for CTC Identification -- 1. Significance of Studying Circulating Tumor Cells -- 2. Affinity-Based Enrichment of Circulating Tumor Cells -- 3. Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Characterization -- 4. Molecular Assays for the Detection and Molecular Characterization of CTCs -- 5. Cancer Stem Cells and Circulating Tumor Cells Molecular Markers, Isolation Techniques and Clinical Implications -- Section II. Fundamental Studies of CTC -- 6. Circulating Tumor Cells and Tumor Dormancy -- 7. Prevention of Conversion of Tumor Dormancy into Proliferative Metastases -- 8. Genesis of Circulating Tumor Cells through Epithelial-Mesenchymal Transition as a Mechanism for Distant Dissemination -- Section III. CTC Analysis -- 9. CTC Analysis FISH, ISH, Array-CGH and Other Molecular Assays -- 10. Genome-Wide Gene Copy Number Analysis of Circulating Tumor Cells -- 11. Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells -- 12. Prognostic Implications of CTC in Breast Cancer -- Section IV. Potential Clinical Applications of CTC -- 13. CTC in Advanced Breast Cancer Prognosis, Monitoring and Clinical Utility -- 14. Evolution of Metastatic Disease: The Need for Monitoring and Emerging Therapeutic Opportunities -- 15. CTC for Biomarker and Companion Diagnostic Development -- 16. Perspectives on Clinical Applications of CTCs -- Index.
520 $a This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers. CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive “liquid biopsy” procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development.There has been rapid progress in the field, fueled by research in basic science, biomedical engineering, and clinical applications. This book presents the latest developments from world-wide leaders, and will be useful for anyone interested in this important and expanding field.
650 0 $a Cancer research. $3 1253664
650 1 4 $a Cancer Research. $3 668358
700 1 $a Cote, Richard J. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1106188
700 1 $a Datar, Ram. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1271624
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9781493933617
776 0 8 $i Printed edition: $z 9781493933624
776 0 8 $i Printed edition: $z 9781493980314
830 0 $a Current Cancer Research, $x 2199-2584 $3 1257028
856 4 0 $u https://doi.org/10.1007/978-1-4939-3363-1
912 $a ZDB-2-SME
912 $a ZDB-2-SXM
950 $a Medicine (SpringerNature-11650)
950 $a Medicine (R0) (SpringerNature-43714)