國立虎尾科技大學 |

DNA Replication, Recombination, and Repair = Molecular Mechanisms and Pathology /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	DNA Replication, Recombination, and Repair/ edited by Fumio Hanaoka, Kaoru Sugasawa.
其他題名:	Molecular Mechanisms and Pathology /
其他作者:	Hanaoka, Fumio.
面頁冊數:	IX, 555 p. 79 illus., 61 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Biochemistry, general. -
電子資源:	https://doi.org/10.1007/978-4-431-55873-6
ISBN:	9784431558736

DNA Replication, Recombination, and Repair = Molecular Mechanisms and Pathology /
DNA Replication, Recombination, and RepairMolecular Mechanisms and Pathology /[electronic resource] :edited by Fumio Hanaoka, Kaoru Sugasawa. - 1st ed. 2016. - IX, 555 p. 79 illus., 61 illus. in color.online resource.

Part 1 DNA Replication -- 1 Molecular Mechanism of DNA Replication -- 2 Characteristics of Metazoan DNA Replication Origins -- 3 DNA Replication Timing: Temporal and Spatial Regulation of Eukaryotic DNA Replication -- Part 2 DNA Recombination -- 4 Mechanism of Homologous Recombination -- 5 Regulation of Recombination by Chromatin -- 6 Homologous Recombination During Meiosis -- Part 3 DNA Repair -- 7 DNA Damage Recognition and Repair in Mammalian Global Genome Nucleotide Excision Repair -- 8 The Fanconi Anemia Pathway and Interstrand Crosslink Repair -- 9 The Crossroads of Ubiquitination and DNA Repair: A Structural Perspective -- Part 4 Genome Instability and Mutagenesis -- 10 Genome Instability of Repetitive Sequence: Lesson From the Ribosomal RNA Gene Repeat -- 11 Translesion DNA Synthesis and Damage Tolerance Pathways -- 12 Mismatch Repair -- 13 Non-Homologous End-Joining -- Part 5 Chromosome Dynamics and Functions -- 14 Centromeric Chromatin and Kinetochore Assembly in Vertebrate Cells -- 15 CST Complex and Telomere Maintenance -- Part 6 Cell Cycle and Checkpoints -- 16 Signaling of DNA Replication Stress Through the ATR Checkpoint -- 17 Spindle Assembly Checkpoint: Its Control and Aberration -- 18 Molecular Insights Into the Regulation of Apoptosis and Cellular Senescence and Their Implications for Cancer -- Part 7 Interplay with Transcription and Epigenetic Regulation -- 19 DNA Replication and Histone M odification -- 20 Establishment and Maintenance of DNA Methylation -- 21 Active DNA Demethylation in Development, Human Disease, and Cancer -- BM Index.

This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.

ISBN: 9784431558736

Standard No.: 10.1007/978-4-431-55873-6doiSubjects--Topical Terms:

593881
Biochemistry, general.

LC Class. No.: QH573-671

Dewey Class. No.: 571.6

DNA Replication, Recombination, and Repair = Molecular Mechanisms and Pathology /
LDR:04840nam a22003975i 4500 001 978106
003 DE-He213
005 20200701121847.0
007 cr nn 008mamaa
008 201211s2016 ja | s |||| 0|eng d
020 $a 9784431558736 $9 978-4-431-55873-6
024 7 $a 10.1007/978-4-431-55873-6 $2 doi
035 $a 978-4-431-55873-6
050 4 $a QH573-671
072 7 $a PSF $2 bicssc
072 7 $a SCI049000 $2 bisacsh
072 7 $a PSF $2 thema
082 0 4 $a 571.6 $2 23
245 1 0 $a DNA Replication, Recombination, and Repair $h [electronic resource] : $b Molecular Mechanisms and Pathology / $c edited by Fumio Hanaoka, Kaoru Sugasawa.
250 $a 1st ed. 2016.
264 1 $a Tokyo : $b Springer Japan : $b Imprint: Springer, $c 2016.
300 $a IX, 555 p. 79 illus., 61 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Part 1 DNA Replication -- 1 Molecular Mechanism of DNA Replication -- 2 Characteristics of Metazoan DNA Replication Origins -- 3 DNA Replication Timing: Temporal and Spatial Regulation of Eukaryotic DNA Replication -- Part 2 DNA Recombination -- 4 Mechanism of Homologous Recombination -- 5 Regulation of Recombination by Chromatin -- 6 Homologous Recombination During Meiosis -- Part 3 DNA Repair -- 7 DNA Damage Recognition and Repair in Mammalian Global Genome Nucleotide Excision Repair -- 8 The Fanconi Anemia Pathway and Interstrand Crosslink Repair -- 9 The Crossroads of Ubiquitination and DNA Repair: A Structural Perspective -- Part 4 Genome Instability and Mutagenesis -- 10 Genome Instability of Repetitive Sequence: Lesson From the Ribosomal RNA Gene Repeat -- 11 Translesion DNA Synthesis and Damage Tolerance Pathways -- 12 Mismatch Repair -- 13 Non-Homologous End-Joining -- Part 5 Chromosome Dynamics and Functions -- 14 Centromeric Chromatin and Kinetochore Assembly in Vertebrate Cells -- 15 CST Complex and Telomere Maintenance -- Part 6 Cell Cycle and Checkpoints -- 16 Signaling of DNA Replication Stress Through the ATR Checkpoint -- 17 Spindle Assembly Checkpoint: Its Control and Aberration -- 18 Molecular Insights Into the Regulation of Apoptosis and Cellular Senescence and Their Implications for Cancer -- Part 7 Interplay with Transcription and Epigenetic Regulation -- 19 DNA Replication and Histone M odification -- 20 Establishment and Maintenance of DNA Methylation -- 21 Active DNA Demethylation in Development, Human Disease, and Cancer -- BM Index.
520 $a This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.
650 2 4 $a Biochemistry, general. $3 593881
650 0 $a Cell biology. $3 1253486
650 0 $a Biochemistry. $3 582831
650 0 $a Pathology. $3 668553
650 0 $a Cytogenetics. $3 798484
650 1 4 $a Cell Biology. $3 593889
700 1 $a Hanaoka, Fumio. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1104578
700 1 $a Sugasawa, Kaoru. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1104579
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9784431558712
776 0 8 $i Printed edition: $z 9784431558729
776 0 8 $i Printed edition: $z 9784431567172
856 4 0 $u https://doi.org/10.1007/978-4-431-55873-6
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)