語系:
繁體中文
English
說明(常見問題)
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Cystogenesis
~
Ahn, Curie.
Cystogenesis
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Cystogenesis/ edited by Jong Hoon Park, Curie Ahn.
其他作者:
Park, Jong Hoon.
面頁冊數:
IX, 126 p.online resource. :
Contained By:
Springer Nature eBook
標題:
Human genetics. -
電子資源:
https://doi.org/10.1007/978-981-10-2041-4
ISBN:
9789811020414
Cystogenesis
Cystogenesis
[electronic resource] /edited by Jong Hoon Park, Curie Ahn. - 1st ed. 2016. - IX, 126 p.online resource. - Advances in Experimental Medicine and Biology,9330065-2598 ;. - Advances in Experimental Medicine and Biology,889.
Part I ADPKD Overview -- Chapter 1 Recent Trends in ADPKD Research -- Chapter 2 Genetic Mechanisms of ADPKD -- Part II Cystogenesis Mechanisms -- Chapter 3 Cell Proliferation and Apoptosis in ADPKD -- Chapter 4 Inflammation and Fibrosis in ADPKD -- Chapter 5 Functional Study of the Primary Cilia in ADPKD -- Chapter 6 Epigenetic Regulation in Cystogenesis -- Part III Therapeutic Approaches and Diagnostic Markers for ADPKD -- Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models -- Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD -- Chapter 9 Clinical Trials and a View toward the Future of ADPKD.
This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease. Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology. This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine.
ISBN: 9789811020414
Standard No.: 10.1007/978-981-10-2041-4doiSubjects--Topical Terms:
596505
Human genetics.
LC Class. No.: RB155-155.8
Dewey Class. No.: 611.01816
Cystogenesis
LDR
:03343nam a22004335i 4500
001
981783
003
DE-He213
005
20200629201526.0
007
cr nn 008mamaa
008
201211s2016 si | s |||| 0|eng d
020
$a
9789811020414
$9
978-981-10-2041-4
024
7
$a
10.1007/978-981-10-2041-4
$2
doi
035
$a
978-981-10-2041-4
050
4
$a
RB155-155.8
050
4
$a
QH431
072
7
$a
MFN
$2
bicssc
072
7
$a
MED107000
$2
bisacsh
072
7
$a
MFN
$2
thema
082
0 4
$a
611.01816
$2
23
082
0 4
$a
599.935
$2
23
245
1 0
$a
Cystogenesis
$h
[electronic resource] /
$c
edited by Jong Hoon Park, Curie Ahn.
250
$a
1st ed. 2016.
264
1
$a
Singapore :
$b
Springer Singapore :
$b
Imprint: Springer,
$c
2016.
300
$a
IX, 126 p.
$b
online resource.
336
$a
text
$b
txt
$2
rdacontent
337
$a
computer
$b
c
$2
rdamedia
338
$a
online resource
$b
cr
$2
rdacarrier
347
$a
text file
$b
PDF
$2
rda
490
1
$a
Advances in Experimental Medicine and Biology,
$x
0065-2598 ;
$v
933
505
0
$a
Part I ADPKD Overview -- Chapter 1 Recent Trends in ADPKD Research -- Chapter 2 Genetic Mechanisms of ADPKD -- Part II Cystogenesis Mechanisms -- Chapter 3 Cell Proliferation and Apoptosis in ADPKD -- Chapter 4 Inflammation and Fibrosis in ADPKD -- Chapter 5 Functional Study of the Primary Cilia in ADPKD -- Chapter 6 Epigenetic Regulation in Cystogenesis -- Part III Therapeutic Approaches and Diagnostic Markers for ADPKD -- Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models -- Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD -- Chapter 9 Clinical Trials and a View toward the Future of ADPKD.
520
$a
This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease. Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology. This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine.
650
0
$a
Human genetics.
$3
596505
650
0
$a
Molecular biology.
$3
583443
650
0
$a
Cell biology.
$3
1253486
650
0
$a
Medical microbiology.
$3
583124
650
1 4
$a
Human Genetics.
$3
593893
650
2 4
$a
Molecular Medicine.
$3
668353
650
2 4
$a
Cell Biology.
$3
593889
650
2 4
$a
Medical Microbiology.
$3
668401
700
1
$a
Park, Jong Hoon.
$4
edt
$4
http://id.loc.gov/vocabulary/relators/edt
$3
1114463
700
1
$a
Ahn, Curie.
$4
edt
$4
http://id.loc.gov/vocabulary/relators/edt
$3
1114464
710
2
$a
SpringerLink (Online service)
$3
593884
773
0
$t
Springer Nature eBook
776
0 8
$i
Printed edition:
$z
9789811020407
776
0 8
$i
Printed edition:
$z
9789811020421
776
0 8
$i
Printed edition:
$z
9789811095115
830
0
$a
Advances in Experimental Medicine and Biology,
$x
0065-2598 ;
$v
889
$3
1253792
856
4 0
$u
https://doi.org/10.1007/978-981-10-2041-4
912
$a
ZDB-2-SBL
912
$a
ZDB-2-SXB
950
$a
Biomedical and Life Sciences (SpringerNature-11642)
950
$a
Biomedical and Life Sciences (R0) (SpringerNature-43708)
筆 0 讀者評論
多媒體
評論
新增評論
分享你的心得
Export
取書館別
處理中
...
變更密碼[密碼必須為2種組合(英文和數字)及長度為10碼以上]
登入