國立虎尾科技大學 |

Antimicrobial Peptides = Role in Human Health and Disease /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Antimicrobial Peptides/ edited by Jürgen Harder, Jens-M. Schröder.
Reminder of title:	Role in Human Health and Disease /
other author:	Harder, Jürgen.
Description:	VI, 158 p. 10 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Immunology. -
Online resource:	https://doi.org/10.1007/978-3-319-24199-9
ISBN:	9783319241999

Antimicrobial Peptides = Role in Human Health and Disease /
Antimicrobial PeptidesRole in Human Health and Disease /[electronic resource] :edited by Jürgen Harder, Jens-M. Schröder. - 1st ed. 2016. - VI, 158 p. 10 illus. in color.online resource. - Birkhäuser Advances in Infectious Diseases,2504-3811. - Birkhäuser Advances in Infectious Diseases,.

Antimicrobial peptides in cutaneous wound healing -- Antimicrobial peptides as endogenous antibacterials and antivirals at the ocular surface -- Function of antimicrobial peptides in lung innate immunity -- Role of antimicrobial peptides to prevent infections in the kidney and urinary tract -- Antimicrobial peptides in the gut -- Metal sequestration: An important contribution of antimicrobial peptides to nutritional immunity -- Regulation of antimicrobial peptide gene expression by vitamin D -- Dichotomous roles of cationic polypeptides targeting HIV -- Antimicrobial peptides in host-defense: functions beyond antimicrobial activity.

This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP to restrict the availability of essential metals to bacteria as an efficient antibacterial strategy in nutritional immunity is discussed in the next chapter. Our current understanding of how vitamin D, the sunshine vitamin, influences AMP-expression and how this can affect our health is also addressed. Last but not least, the role of AMP in HIV infection and the immunomodulatory properties of AMP highlight the diverse facets of AMP in host immunity. AMP’s specific functions, including in fighting multi-resistant bacteria, suggest that they may offer therapeutic benefits – a question that is discussed in the final chapter.

ISBN: 9783319241999

Standard No.: 10.1007/978-3-319-24199-9doiSubjects--Topical Terms:

592892
Immunology.

LC Class. No.: QR180-189.5

Dewey Class. No.: 616.079

Antimicrobial Peptides = Role in Human Health and Disease /
LDR:03266nam a22004095i 4500 001 981913
003 DE-He213
005 20200702163942.0
007 cr nn 008mamaa
008 201211s2016 gw | s |||| 0|eng d
020 $a 9783319241999 $9 978-3-319-24199-9
024 7 $a 10.1007/978-3-319-24199-9 $2 doi
035 $a 978-3-319-24199-9
050 4 $a QR180-189.5
072 7 $a MJCM $2 bicssc
072 7 $a MED044000 $2 bisacsh
072 7 $a MJCM $2 thema
082 0 4 $a 616.079 $2 23
245 1 0 $a Antimicrobial Peptides $h [electronic resource] : $b Role in Human Health and Disease / $c edited by Jürgen Harder, Jens-M. Schröder.
250 $a 1st ed. 2016.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a VI, 158 p. 10 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Birkhäuser Advances in Infectious Diseases, $x 2504-3811
505 0 $a Antimicrobial peptides in cutaneous wound healing -- Antimicrobial peptides as endogenous antibacterials and antivirals at the ocular surface -- Function of antimicrobial peptides in lung innate immunity -- Role of antimicrobial peptides to prevent infections in the kidney and urinary tract -- Antimicrobial peptides in the gut -- Metal sequestration: An important contribution of antimicrobial peptides to nutritional immunity -- Regulation of antimicrobial peptide gene expression by vitamin D -- Dichotomous roles of cationic polypeptides targeting HIV -- Antimicrobial peptides in host-defense: functions beyond antimicrobial activity.
520 $a This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP to restrict the availability of essential metals to bacteria as an efficient antibacterial strategy in nutritional immunity is discussed in the next chapter. Our current understanding of how vitamin D, the sunshine vitamin, influences AMP-expression and how this can affect our health is also addressed. Last but not least, the role of AMP in HIV infection and the immunomodulatory properties of AMP highlight the diverse facets of AMP in host immunity. AMP’s specific functions, including in fighting multi-resistant bacteria, suggest that they may offer therapeutic benefits – a question that is discussed in the final chapter.
650 0 $a Immunology. $3 592892
650 0 $a Microbiology. $3 591510
700 1 $a Harder, Jürgen. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1274177
700 1 $a Schröder, Jens-M. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1274178
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319241975
776 0 8 $i Printed edition: $z 9783319241982
776 0 8 $i Printed edition: $z 9783319795881
830 0 $a Birkhäuser Advances in Infectious Diseases, $x 2504-3811 $3 1271258
856 4 0 $u https://doi.org/10.1007/978-3-319-24199-9
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)