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The Search for Human Chromosomes = A History of Discovery /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The Search for Human Chromosomes/ by Wilson John Wall.
Reminder of title:	A History of Discovery /
Author:	Wall, Wilson John.
Description:	VII, 179 p. 48 illus., 28 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	History. -
Online resource:	https://doi.org/10.1007/978-3-319-26336-6
ISBN:	9783319263366

The Search for Human Chromosomes = A History of Discovery /
Wall, Wilson John.

The Search for Human ChromosomesA History of Discovery /[electronic resource] :by Wilson John Wall. - 1st ed. 2016. - VII, 179 p. 48 illus., 28 illus. in color.online resource.

Introduction -- Background to the Hunt for the Human Chromosome Number -- Microscopes and Stains: The Rise of Technology -- Mendel and Genetics -- Chromosomes as the Carriers of Heredity -- Difficulties of Chromosome Handling and Access to Material -- The Implications of DNA Structure -- Tissue Culture and the Cell Cycle: The Answer is Revealed -- The Flowering of Clinical Genetics -- Sex and Chromosomes -- What we Know, What we Don’t and Where This may Lead us -- Appendix A: Rough Guide to Chromosome Structure -- Appendix B: People in the Text -- Glossary.

This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book.

ISBN: 9783319263366

Standard No.: 10.1007/978-3-319-26336-6doiSubjects--Topical Terms:

669538
History.

LC Class. No.: D1-DX301

Dewey Class. No.: 509

The Search for Human Chromosomes = A History of Discovery /
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505 0 $a Introduction -- Background to the Hunt for the Human Chromosome Number -- Microscopes and Stains: The Rise of Technology -- Mendel and Genetics -- Chromosomes as the Carriers of Heredity -- Difficulties of Chromosome Handling and Access to Material -- The Implications of DNA Structure -- Tissue Culture and the Cell Cycle: The Answer is Revealed -- The Flowering of Clinical Genetics -- Sex and Chromosomes -- What we Know, What we Don’t and Where This may Lead us -- Appendix A: Rough Guide to Chromosome Structure -- Appendix B: People in the Text -- Glossary.
520 $a This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book.
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