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Introduction to Synthetic Biology = About Modeling, Computation, and Circuit Design /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Introduction to Synthetic Biology/ by Mario Andrea Marchisio.
Reminder of title:	About Modeling, Computation, and Circuit Design /
Author:	Marchisio, Mario Andrea.
Description:	XII, 187 p. 91 illus., 74 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Biomedical engineering. -
Online resource:	https://doi.org/10.1007/978-981-10-8752-3
ISBN:	9789811087523

Introduction to Synthetic Biology = About Modeling, Computation, and Circuit Design /
Marchisio, Mario Andrea.

Introduction to Synthetic BiologyAbout Modeling, Computation, and Circuit Design /[electronic resource] :by Mario Andrea Marchisio. - 1st ed. 2018. - XII, 187 p. 91 illus., 74 illus. in color.online resource. - Learning Materials in Biosciences,2509-6125. - Learning Materials in Biosciences,1.

Chapter 1: Introduction -- Chapter 2: Modeling: choosing a kinetics -- Chapter 3: Modeling at computer: getting started -- Chapter 4: Stochastic modeling -- Chapter 5: Steady states -- Chapter 6: Stability analysis: hysteresis and oscillations -- Chapter7: Toggle switch: dynamics and steady states -- Chapter 8: Rule-based modeling -- Chapter 9: Gene circuit modular computational design -- Chapter 10: Parameter analysis -- Chapter 11: Circuit analysis with COPASI -- Chapter 12: Circuit motifs.

The textbook is based on the lectures of the course “Synthetic Biology” for Master’s students in biology and biotechnology at the Harbin Institute of Technology. The goal of the textbook is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab. Concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis and optimization are presented. At the end of the textbook, a chapter contains a description of structural motifs (e.g. positive and negative feedback loops, Boolean gates) that carry out specific functions and can be combined into larger networks. Moreover, several chapters show how to build up (an analyse, where possible) models for synthetic gene circuits with four different open-source software i.e. COPASI, XPPAUT, BioNetGeN, and Parts & Pools-ProMoT.

ISBN: 9789811087523

Standard No.: 10.1007/978-981-10-8752-3doiSubjects--Topical Terms:

588770
Biomedical engineering.

LC Class. No.: R856-R857

Dewey Class. No.: 610.28

Introduction to Synthetic Biology = About Modeling, Computation, and Circuit Design /
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