國立虎尾科技大學 |

Role of Tyrosine Kinases in Gastrointestinal Malignancies

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Role of Tyrosine Kinases in Gastrointestinal Malignancies/ edited by Ganji Purnachandra Nagaraju.
其他作者:	Nagaraju, Ganji Purnachandra.
面頁冊數:	XV, 241 p. 28 illus., 21 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Cancer research. -
電子資源:	https://doi.org/10.1007/978-981-13-1486-5
ISBN:	9789811314865

Role of Tyrosine Kinases in Gastrointestinal Malignancies
Role of Tyrosine Kinases in Gastrointestinal Malignancies[electronic resource] /edited by Ganji Purnachandra Nagaraju. - 1st ed. 2018. - XV, 241 p. 28 illus., 21 illus. in color.online resource.

Chapter 1. 1. Overview of tyrosine kinases and their receptors in gastrointestinal malignancies- -- Chapter 2. EGFR and Erb-B2R (HER2): their role in Esophagus cancer -- Chapter 3. HGFR and FGFR2: their role in progression and metastasis of Esophagus cancer -- Chapter 4. Role of Src and VEGF R tyrosine kinases in Esophagus cancer -- Chapter 5. HGF receptor tyrosine kinase in gastric cancer. - Chapter 6. The EGF/ErbB receptor family of tyrosine kinases in gastric cancer -- Chapter 7. Helicobacter pylori CagA protein: its role and interaction tyrosine kinases in gastric cancer -- Chapter 8. RON receptor tyrosine kinase in pancreatic cancer progression -- Chapter 9. EGFR and Cytoplasmic kinases Src targeting in pancreatic cancer -- Chapter 10. VEGF and PDGFR targeting in pancreatic cancer -- Chapter 11. c-KIT, and FLT-3: their role in Hepatocellular carcinoma -- Chapter 12. VEGFR, and PDGFR: their targeting in Liver Cancer -- Chapter 13. EGFR and FGFR in growth and metastasis of colorectal cancer -- Chapter 14. VEGFR, and PDGFR: their targeting in colorectal cancerm -- Chapter 15. Nano materials and their impact on tyrosine kinase on selected gastrointestinal malignancies -- Chapter 16. Tyrosine kinase inhibitors and their clinical prospective in gastrointestinal malignancies -- Chapter 17. Drug resistance against tyrosine kinase inhibitors in gastrointestinal malignancies -- Chapter 18. Tyrosine kinases: their expression, diagnostic, therapeutic and prognostic aspects in gastrointestinal cancers.

The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy. Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.

ISBN: 9789811314865

Standard No.: 10.1007/978-981-13-1486-5doiSubjects--Topical Terms:

1253664
Cancer research.

LC Class. No.: RC261-271

Dewey Class. No.: 614.5999

Role of Tyrosine Kinases in Gastrointestinal Malignancies
LDR:03772nam a22003975i 4500 001 989067
003 DE-He213
005 20200702025904.0
007 cr nn 008mamaa
008 201225s2018 si | s |||| 0|eng d
020 $a 9789811314865 $9 978-981-13-1486-5
024 7 $a 10.1007/978-981-13-1486-5 $2 doi
035 $a 978-981-13-1486-5
050 4 $a RC261-271
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 614.5999 $2 23
245 1 0 $a Role of Tyrosine Kinases in Gastrointestinal Malignancies $h [electronic resource] / $c edited by Ganji Purnachandra Nagaraju.
250 $a 1st ed. 2018.
264 1 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2018.
300 $a XV, 241 p. 28 illus., 21 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Chapter 1. 1. Overview of tyrosine kinases and their receptors in gastrointestinal malignancies- -- Chapter 2. EGFR and Erb-B2R (HER2): their role in Esophagus cancer -- Chapter 3. HGFR and FGFR2: their role in progression and metastasis of Esophagus cancer -- Chapter 4. Role of Src and VEGF R tyrosine kinases in Esophagus cancer -- Chapter 5. HGF receptor tyrosine kinase in gastric cancer. - Chapter 6. The EGF/ErbB receptor family of tyrosine kinases in gastric cancer -- Chapter 7. Helicobacter pylori CagA protein: its role and interaction tyrosine kinases in gastric cancer -- Chapter 8. RON receptor tyrosine kinase in pancreatic cancer progression -- Chapter 9. EGFR and Cytoplasmic kinases Src targeting in pancreatic cancer -- Chapter 10. VEGF and PDGFR targeting in pancreatic cancer -- Chapter 11. c-KIT, and FLT-3: their role in Hepatocellular carcinoma -- Chapter 12. VEGFR, and PDGFR: their targeting in Liver Cancer -- Chapter 13. EGFR and FGFR in growth and metastasis of colorectal cancer -- Chapter 14. VEGFR, and PDGFR: their targeting in colorectal cancerm -- Chapter 15. Nano materials and their impact on tyrosine kinase on selected gastrointestinal malignancies -- Chapter 16. Tyrosine kinase inhibitors and their clinical prospective in gastrointestinal malignancies -- Chapter 17. Drug resistance against tyrosine kinase inhibitors in gastrointestinal malignancies -- Chapter 18. Tyrosine kinases: their expression, diagnostic, therapeutic and prognostic aspects in gastrointestinal cancers.
520 $a The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy. Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.
650 0 $a Cancer research. $3 1253664
650 0 $a Human physiology. $3 636012
650 0 $a Cell biology. $3 1253486
650 0 $a Proteins . $3 1253493
650 0 $a Gene expression. $3 581931
650 0 $a Oncology . $3 1253469
650 1 4 $a Cancer Research. $3 668358
650 2 4 $a Human Physiology. $3 668349
650 2 4 $a Cell Biology. $3 593889
650 2 4 $a Receptors. $3 787639
650 2 4 $a Gene Expression. $3 582691
650 2 4 $a Oncology. $3 593951
700 1 $a Nagaraju, Ganji Purnachandra. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1198408
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9789811314858
776 0 8 $i Printed edition: $z 9789811314872
776 0 8 $i Printed edition: $z 9789811346408
856 4 0 $u https://doi.org/10.1007/978-981-13-1486-5
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)