國立虎尾科技大學 |

Systems Biology

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Systems Biology/ edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski.
其他作者:	Rajewsky, Nikolaus.
面頁冊數:	X, 401 p. 60 illus., 46 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Systems biology. -
電子資源:	https://doi.org/10.1007/978-3-319-92967-5
ISBN:	9783319929675

Systems Biology
Systems Biology[electronic resource] /edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski. - 1st ed. 2018. - X, 401 p. 60 illus., 46 illus. in color.online resource. - RNA Technologies,2197-9731. - RNA Technologies,.

Chapter 1: Systems Biology of Genome Structure and Dynamics -- Chapter 2: A Systems Perspective of Complex Diseases: from Reductionism to Integration -- Chapter 3: Systems Biology of Bacterial Immune Systems: Regulation of Restriction-Modification and CRISPR-Cas Systems -- Chapter 4: Systems Biology of RNA Binding Proteins in Amyotrophic Lateral Sclerosis -- Chapter 5: Systems Approaches to Map in vivo RNA-Protein Interactions in Arabidopsis thaliana -- Chapter 6: Systems-Level Analysis of Bacterial Regulatory Small RNA Networks -- Chapter 7: Epioncogenes in Cancer—Identification of Transcriptomic and Epigenomic Cooperation Networks by Multi-Omics Integration of RNA-Seq and ChIP-Seqdata -- Chapter 8: Coupling Large Scale –Omics Data for Deciphering Systems Complexity -- Chapter 9: Deciphering the Universe of RNA Structures and tTans RNA-RNA Interactions of Transcriptomes in vivo | from Experimental Protocols to Computational Analyses -- Chapter 10: Is Autogenous Post-Transcriptional Gene Regulation Common? -- Chapter 11: The Interplay of Non-Coding RNAs and X Chromosome Inactivation in Human Disease -- Chapter 12: Novel Insights of the Gene Translational Dynamic and Complex Revealed by Ribosome Profiling -- Chapter 13: Biophysical Analysis of MiRNA-Dependent Gene Regulation -- Chapter 14: Modeling and Analyzing the Flow of Molecular Machines in Gene Expression -- Chapter 15: Robust Approaches to Generating Reliable Predictive Models in Systems Biology -- Chapter 16: Hints from Information Theory for Analyzing Dynamic & High Dimensional Biological Data -- Chapter 17: Enhancing Metabolic Models with Genome-Scale Experimental Data -- Chapter 18: An Integrative MuSiCO Algorithm: from the Patient-Specific Transcriptional Profiles to Novel Checkpoints in Disease Pathobiology -- Chapter 19: Nanocellulose: a New Multifunctional Tool for RNA System Biology Research.

Many breakthroughs in experimental devices, advanced software, as well as analytical methods for systems biology development have helped shape the way we study DNA, RNA and proteins, on the genomic, transcriptional, translational and posttranslational level. This book highlights the comprehensive topics that encompass systems biology with enormous progress in the development of genome sequencing, proteomic and metabolomic methods in designing and understanding biological systems. Topics covered in this book include fundamentals of modelling networks, circuits and pathways, spatial and multi cellular systems, image-driven systems biology, evolution, noise and decision-making in single cells, systems biology of disease and immunology, and personalized medicine. Special attention is paid to epigenomics, in particular environmental conditions that impact genetic background. The breadth of exciting new data towards discovering fundamental principles and direct application of epigenetics in agriculture is also described. The chapter “Deciphering the Universe of RNA Structures and Trans RNA-RNA Interactions of Transcriptomes in vivo - from Experimental Protocols to Computational Analyses” is available open access under a CC BY 4.0 license via link.springer.com.

ISBN: 9783319929675

Standard No.: 10.1007/978-3-319-92967-5doiSubjects--Topical Terms:

600045
Systems biology.

LC Class. No.: QH301-705

Dewey Class. No.: 570

Systems Biology
LDR:04580nam a22004095i 4500 001 989152
003 DE-He213
005 20200705032842.0
007 cr nn 008mamaa
008 201225s2018 gw | s |||| 0|eng d
020 $a 9783319929675 $9 978-3-319-92967-5
024 7 $a 10.1007/978-3-319-92967-5 $2 doi
035 $a 978-3-319-92967-5
050 4 $a QH301-705
072 7 $a PSA $2 bicssc
072 7 $a SCI086000 $2 bisacsh
072 7 $a PSA $2 thema
082 0 4 $a 570 $2 23
245 1 0 $a Systems Biology $h [electronic resource] / $c edited by Nikolaus Rajewsky, Stefan Jurga, Jan Barciszewski.
250 $a 1st ed. 2018.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a X, 401 p. 60 illus., 46 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a RNA Technologies, $x 2197-9731
505 0 $a Chapter 1: Systems Biology of Genome Structure and Dynamics -- Chapter 2: A Systems Perspective of Complex Diseases: from Reductionism to Integration -- Chapter 3: Systems Biology of Bacterial Immune Systems: Regulation of Restriction-Modification and CRISPR-Cas Systems -- Chapter 4: Systems Biology of RNA Binding Proteins in Amyotrophic Lateral Sclerosis -- Chapter 5: Systems Approaches to Map in vivo RNA-Protein Interactions in Arabidopsis thaliana -- Chapter 6: Systems-Level Analysis of Bacterial Regulatory Small RNA Networks -- Chapter 7: Epioncogenes in Cancer—Identification of Transcriptomic and Epigenomic Cooperation Networks by Multi-Omics Integration of RNA-Seq and ChIP-Seqdata -- Chapter 8: Coupling Large Scale –Omics Data for Deciphering Systems Complexity -- Chapter 9: Deciphering the Universe of RNA Structures and tTans RNA-RNA Interactions of Transcriptomes in vivo | from Experimental Protocols to Computational Analyses -- Chapter 10: Is Autogenous Post-Transcriptional Gene Regulation Common? -- Chapter 11: The Interplay of Non-Coding RNAs and X Chromosome Inactivation in Human Disease -- Chapter 12: Novel Insights of the Gene Translational Dynamic and Complex Revealed by Ribosome Profiling -- Chapter 13: Biophysical Analysis of MiRNA-Dependent Gene Regulation -- Chapter 14: Modeling and Analyzing the Flow of Molecular Machines in Gene Expression -- Chapter 15: Robust Approaches to Generating Reliable Predictive Models in Systems Biology -- Chapter 16: Hints from Information Theory for Analyzing Dynamic & High Dimensional Biological Data -- Chapter 17: Enhancing Metabolic Models with Genome-Scale Experimental Data -- Chapter 18: An Integrative MuSiCO Algorithm: from the Patient-Specific Transcriptional Profiles to Novel Checkpoints in Disease Pathobiology -- Chapter 19: Nanocellulose: a New Multifunctional Tool for RNA System Biology Research.
520 $a Many breakthroughs in experimental devices, advanced software, as well as analytical methods for systems biology development have helped shape the way we study DNA, RNA and proteins, on the genomic, transcriptional, translational and posttranslational level. This book highlights the comprehensive topics that encompass systems biology with enormous progress in the development of genome sequencing, proteomic and metabolomic methods in designing and understanding biological systems. Topics covered in this book include fundamentals of modelling networks, circuits and pathways, spatial and multi cellular systems, image-driven systems biology, evolution, noise and decision-making in single cells, systems biology of disease and immunology, and personalized medicine. Special attention is paid to epigenomics, in particular environmental conditions that impact genetic background. The breadth of exciting new data towards discovering fundamental principles and direct application of epigenetics in agriculture is also described. The chapter “Deciphering the Universe of RNA Structures and Trans RNA-RNA Interactions of Transcriptomes in vivo - from Experimental Protocols to Computational Analyses” is available open access under a CC BY 4.0 license via link.springer.com.
650 0 $a Systems biology. $3 600045
650 0 $a Human genetics. $3 596505
650 0 $a Molecular biology. $3 583443
650 0 $a Nucleic acids. $3 788506
650 0 $a Biomedical engineering. $3 588770
650 1 4 $a Systems Biology. $3 683756
650 2 4 $a Human Genetics. $3 593893
650 2 4 $a Molecular Medicine. $3 668353
650 2 4 $a Nucleic Acid Chemistry. $3 716485
650 2 4 $a Biomedical Engineering/Biotechnology. $3 1068811
700 1 $a Rajewsky, Nikolaus. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1140998
700 1 $a Jurga, Stefan. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1111135
700 1 $a Barciszewski, Jan. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 681349
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319929668
776 0 8 $i Printed edition: $z 9783319929682
776 0 8 $i Printed edition: $z 9783030065591
830 0 $a RNA Technologies, $x 2197-9731 $3 1266093
856 4 0 $u https://doi.org/10.1007/978-3-319-92967-5
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)