國立虎尾科技大學 |

Heat Shock Proteins in the Immune System

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Heat Shock Proteins in the Immune System/ edited by Robert J. Binder, Pramod K. Srivastava.
其他作者:	Binder, Robert J.
面頁冊數:	X, 185 p. 22 illus., 20 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Immunology. -
電子資源:	https://doi.org/10.1007/978-3-319-69042-1
ISBN:	9783319690421

Heat Shock Proteins in the Immune System
Heat Shock Proteins in the Immune System[electronic resource] /edited by Robert J. Binder, Pramod K. Srivastava. - 1st ed. 2018. - X, 185 p. 22 illus., 20 illus. in color.online resource.

Introduction and history.- Part I: Structure of the HSPs in relation to chaperoning peptides and proteins -- Chapter 1: Hsp70-subsrate interactions -- Chapter 2: Molecular Chaperone Inhibitors.- Part II: Exposure of HSPs to immune cells -- Chapter 3: Extracellular Heat Shock Proteins as Stress Communication Signals.- Part III: Regulation of immune responses by extracellular HSPs -- Chapter 4: The Heat Shock Protein-CD91 pathway and Tumor Immuno-surveillance -- Chapter 5: Bridging the gaps in the vaccine development: Avant-garde vaccine approach with secreted heat shock protein gp96-Ig -- Chapter 6: Regulation of the Extracellular Matrix by Heat Shock Proteins and Molecular Chaperones -- Chapter 7: Heat shock protein mediated T cell responses in pathogen infections -- Chapter 8: An ancestral immune surveillance system in the amphibian Xenopus connecting certain heat shock proteins with classical and nonclassical MHC class I molecules -- Chapter 9: Inhibition of HSPs for Enhanced Immunity. .

Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system. This one-stop resource contains numerous images to both help illustrate the research on heat shock proteins, and better clarify the field for the non-expert. Heat shock proteins (HSPs) were discovered in 1962 and were quickly recognized for their role in protecting cells from stress. Twenty years later, the immunogenicity of a select few HSPs was described, and for the past 30 years, these findings have been applied to numerous branches of immunology, including tumor immunology and immunosurveillance, immunotherapy, etiology of autoimmunity, immunotherapy of infectious diseases, and expression of innate receptors. While HSPs can be used to manipulate immune responses by exogenous administration, they appear to be involved in initiation of de novo immune responses to cancer and likely in the maintenance of immune homeostasis. .

ISBN: 9783319690421

Standard No.: 10.1007/978-3-319-69042-1doiSubjects--Topical Terms:

592892
Immunology.

LC Class. No.: QR180-189.5

Dewey Class. No.: 616.079

Heat Shock Proteins in the Immune System
LDR:03496nam a22003975i 4500 001 989480
003 DE-He213
005 20200707031416.0
007 cr nn 008mamaa
008 201225s2018 gw | s |||| 0|eng d
020 $a 9783319690421 $9 978-3-319-69042-1
024 7 $a 10.1007/978-3-319-69042-1 $2 doi
035 $a 978-3-319-69042-1
050 4 $a QR180-189.5
072 7 $a MJCM $2 bicssc
072 7 $a MED044000 $2 bisacsh
072 7 $a MJCM $2 thema
082 0 4 $a 616.079 $2 23
245 1 0 $a Heat Shock Proteins in the Immune System $h [electronic resource] / $c edited by Robert J. Binder, Pramod K. Srivastava.
250 $a 1st ed. 2018.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a X, 185 p. 22 illus., 20 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Introduction and history.- Part I: Structure of the HSPs in relation to chaperoning peptides and proteins -- Chapter 1: Hsp70-subsrate interactions -- Chapter 2: Molecular Chaperone Inhibitors.- Part II: Exposure of HSPs to immune cells -- Chapter 3: Extracellular Heat Shock Proteins as Stress Communication Signals.- Part III: Regulation of immune responses by extracellular HSPs -- Chapter 4: The Heat Shock Protein-CD91 pathway and Tumor Immuno-surveillance -- Chapter 5: Bridging the gaps in the vaccine development: Avant-garde vaccine approach with secreted heat shock protein gp96-Ig -- Chapter 6: Regulation of the Extracellular Matrix by Heat Shock Proteins and Molecular Chaperones -- Chapter 7: Heat shock protein mediated T cell responses in pathogen infections -- Chapter 8: An ancestral immune surveillance system in the amphibian Xenopus connecting certain heat shock proteins with classical and nonclassical MHC class I molecules -- Chapter 9: Inhibition of HSPs for Enhanced Immunity. .
520 $a Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system. This one-stop resource contains numerous images to both help illustrate the research on heat shock proteins, and better clarify the field for the non-expert. Heat shock proteins (HSPs) were discovered in 1962 and were quickly recognized for their role in protecting cells from stress. Twenty years later, the immunogenicity of a select few HSPs was described, and for the past 30 years, these findings have been applied to numerous branches of immunology, including tumor immunology and immunosurveillance, immunotherapy, etiology of autoimmunity, immunotherapy of infectious diseases, and expression of innate receptors. While HSPs can be used to manipulate immune responses by exogenous administration, they appear to be involved in initiation of de novo immune responses to cancer and likely in the maintenance of immune homeostasis. .
650 0 $a Immunology. $3 592892
650 0 $a Proteins . $3 1253493
650 0 $a Infectious diseases. $3 1102043
650 0 $a Cancer research. $3 1253664
650 2 4 $a Protein Science. $3 782127
650 2 4 $a Infectious Diseases. $3 668393
650 2 4 $a Cancer Research. $3 668358
700 1 $a Binder, Robert J. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1201660
700 1 $a Srivastava, Pramod K. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1201661
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319690407
776 0 8 $i Printed edition: $z 9783319690414
776 0 8 $i Printed edition: $z 9783030098629
856 4 0 $u https://doi.org/10.1007/978-3-319-69042-1
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)