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Bone Marrow Failure

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Bone Marrow Failure/ edited by Gary M. Kupfer, Gregory H. Reaman, Franklin O. Smith.
other author:	Kupfer, Gary M.
Description:	IX, 214 p. 19 illus., 12 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Oncology . -
Online resource:	https://doi.org/10.1007/978-3-319-61421-2
ISBN:	9783319614212

Bone Marrow Failure
Bone Marrow Failure[electronic resource] /edited by Gary M. Kupfer, Gregory H. Reaman, Franklin O. Smith. - 1st ed. 2018. - IX, 214 p. 19 illus., 12 illus. in color.online resource. - Pediatric Oncology,1613-5318. - Pediatric Oncology,.

1. The Cellular and Molecular Mechanisms of Hematopoiesis -- 2. Acquired Aplastic Anemia -- 3. Pediatric Myelodysplastic Syndromes -- 4. Fanconi Anemia: A Pathway of Hematopoeisis and Cancer Predisposition -- 5. Ribosomopathies Through a Diamond Lens -- 6. Dyskeratosis Congenita and the Telomere Biology Disorders -- 7. Diamond Blackfan Anemia -- 8. Shwachman-Diamond Syndrome -- 9. Hematopoietic Cell Transplantation for the Treatment of Patients with Bone Marrow Failure Syndromes -- 10. Inherited Neutropenias and Their Insights into Cellular and Developmental Biology -- 11. Inherited Thrombocytopenias.

This book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques. The full range of relevant conditions is covered, including acquired aplastic anemia, Fanconi anemia, ribosomopathies, telomeropathies, dyskeratosis congenita, Shwachman-Diamond syndrome, Diamond-Blackfan anemia, and congenital neutropenias and thrombocytopenias. In addition, it is explained how the study of these rare diseases has uncovered important new science and elucidated the pathophysiology of more common hematological and oncological diseases. A treatment-specific chapter describes options ranging from the conventional to the cutting edge. Bone Marrow Failure will be of value for both trainee and practicing hematologists and oncologists.

ISBN: 9783319614212

Standard No.: 10.1007/978-3-319-61421-2doiSubjects--Topical Terms:

1253469
Oncology .

LC Class. No.: RC254-282

Dewey Class. No.: 616.994

Bone Marrow Failure
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