國立虎尾科技大學 |

HIV-1 Latency

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	HIV-1 Latency/ edited by Guido Silvestri, Mathias Lichterfeld.
其他作者:	Silvestri, Guido.
面頁冊數:	VII, 248 p.online resource. :
Contained By:	Springer Nature eBook
標題:	Immunology. -
電子資源:	https://doi.org/10.1007/978-3-030-02816-9
ISBN:	9783030028169

HIV-1 Latency
HIV-1 Latency[electronic resource] /edited by Guido Silvestri, Mathias Lichterfeld. - 1st ed. 2018. - VII, 248 p.online resource. - Current Topics in Microbiology and Immunology,4170070-217X ;. - Current Topics in Microbiology and Immunology,387.

Molecular Control of HIV and SIV Latency -- Assays to Measure Latency, Reservoirs and Reactivation -- The Antiviral Immune Response and its Impact on the HIV-1 Reservoir -- Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy -- SIV Latency in Macrophages in the CNS -- Mathematical models of HIV latency -- Residual Immune Activation and Latency -- Immune Interventions to Eliminate the HIV Reservoir -- Cell and Gene Therapy for HIV Cure.

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

ISBN: 9783030028169

Standard No.: 10.1007/978-3-030-02816-9doiSubjects--Topical Terms:

592892
Immunology.

LC Class. No.: QR180-189.5

Dewey Class. No.: 616.079

HIV-1 Latency
LDR:02906nam a22004095i 4500 001 989910
003 DE-He213
005 20200705100336.0
007 cr nn 008mamaa
008 201225s2018 gw | s |||| 0|eng d
020 $a 9783030028169 $9 978-3-030-02816-9
024 7 $a 10.1007/978-3-030-02816-9 $2 doi
035 $a 978-3-030-02816-9
050 4 $a QR180-189.5
072 7 $a MJCM $2 bicssc
072 7 $a MED044000 $2 bisacsh
072 7 $a MJCM $2 thema
082 0 4 $a 616.079 $2 23
245 1 0 $a HIV-1 Latency $h [electronic resource] / $c edited by Guido Silvestri, Mathias Lichterfeld.
250 $a 1st ed. 2018.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a VII, 248 p. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Current Topics in Microbiology and Immunology, $x 0070-217X ; $v 417
505 0 $a Molecular Control of HIV and SIV Latency -- Assays to Measure Latency, Reservoirs and Reactivation -- The Antiviral Immune Response and its Impact on the HIV-1 Reservoir -- Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy -- SIV Latency in Macrophages in the CNS -- Mathematical models of HIV latency -- Residual Immune Activation and Latency -- Immune Interventions to Eliminate the HIV Reservoir -- Cell and Gene Therapy for HIV Cure.
520 $a This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
650 0 $a Immunology. $3 592892
650 0 $a Virology. $3 644995
650 0 $a Pathology. $3 668553
650 0 $a Epidemiology. $3 635923
700 1 $a Silvestri, Guido. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1210062
700 1 $a Lichterfeld, Mathias. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1210063
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783030028152
776 0 8 $i Printed edition: $z 9783030028176
776 0 8 $i Printed edition: $z 9783030132149
830 0 $a Current Topics in Microbiology and Immunology, $x 0070-217X ; $v 387 $3 1254330
856 4 0 $u https://doi.org/10.1007/978-3-030-02816-9
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)