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Modeling Methods for Medical Systems Biology = Regulatory Dynamics Underlying the Emergence of Disease Processes /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Modeling Methods for Medical Systems Biology/ by María Elena Álvarez-Buylla Roces, Juan Carlos Martínez-García, José Dávila-Velderrain, Elisa Domínguez-Hüttinger, Mariana Esther Martínez-Sánchez.
其他題名:	Regulatory Dynamics Underlying the Emergence of Disease Processes /
作者:	Álvarez-Buylla Roces, María Elena.
其他作者:	Martínez-García, Juan Carlos.
面頁冊數:	XXI, 258 p. 60 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Systems biology. -
電子資源:	https://doi.org/10.1007/978-3-319-89354-9
ISBN:	9783319893549

Modeling Methods for Medical Systems Biology = Regulatory Dynamics Underlying the Emergence of Disease Processes /
Álvarez-Buylla Roces, María Elena.

Modeling Methods for Medical Systems BiologyRegulatory Dynamics Underlying the Emergence of Disease Processes /[electronic resource] :by María Elena Álvarez-Buylla Roces, Juan Carlos Martínez-García, José Dávila-Velderrain, Elisa Domínguez-Hüttinger, Mariana Esther Martínez-Sánchez. - 1st ed. 2018. - XXI, 258 p. 60 illus. in color.online resource. - Advances in Experimental Medicine and Biology,10690065-2598 ;. - Advances in Experimental Medicine and Biology,889.

Introduction -- Medical systems biology -- Modeling procedures -- Case of study -- Conclusions and Perspectives -- Bibliography.

This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.

ISBN: 9783319893549

Standard No.: 10.1007/978-3-319-89354-9doiSubjects--Topical Terms:

600045
Systems biology.

LC Class. No.: QH301-705

Dewey Class. No.: 570

Modeling Methods for Medical Systems Biology = Regulatory Dynamics Underlying the Emergence of Disease Processes /
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