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Stereoselective Heterocycle Synthesis via Alkene Difunctionalization = Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Stereoselective Heterocycle Synthesis via Alkene Difunctionalization/ by David A. Petrone.
Reminder of title:	Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation /
Author:	Petrone, David A.
Description:	XXIX, 365 p. 167 illus., 12 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Organometallic chemistry . -
Online resource:	https://doi.org/10.1007/978-3-319-77507-4
ISBN:	9783319775074

Stereoselective Heterocycle Synthesis via Alkene Difunctionalization = Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation /
Petrone, David A.

Stereoselective Heterocycle Synthesis via Alkene DifunctionalizationBulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation /[electronic resource] :by David A. Petrone. - 1st ed. 2018. - XXIX, 365 p. 167 illus., 12 illus. in color.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.

Diastereoselective Synthesis of Heterocycles via Intramolecular Pd-Catalyzed Alkene Aryliodination -- Pd-Catalyzed Diastereoselective Carbocyanation Reactions of Chiral N-Allyl Carboxamides and Indoles -- Development of a Pd-Catalyzed Dearomative 1,2-Diarylation of Indoles using Aryl Boron Reagents -- Harnessing Reversible Oxidative Addition: Application of Diiodinated Aromatic Compounds in Aryliodination.

This book investigates the use of palladium modified by bulky ligands as catalysts for new chemical transformations that rapidly assemble several classes of complex heterocyles. It documents the development of new chemical reactions involving carbon–carbon (C‒C) and carbon–halogen (C‒X) bond formation in the context of alkene difunctionalization and dearomatization reactions. Due to the ubiquity of heterocycles in bioactive natural products and life-improving pharmaceutical treatments, a long-term goal for synthetic organic chemists has been to develop novel and creative heterocycle syntheses that illicit a high degree of product diversity and are characterized by mild reaction conditions and limited waste production. A considerable fraction of leading pharmaceutical drugs contain at least one heterocycle within their chemical structure, and their prevalence in these technologies is strong evidence that the fundamental curiosities of organic chemistry lead to real-world solutions for the health and wellness of the global population.

ISBN: 9783319775074

Standard No.: 10.1007/978-3-319-77507-4doiSubjects--Topical Terms:

1254952
Organometallic chemistry .

LC Class. No.: QD410-412.5

Dewey Class. No.: 547.05

Stereoselective Heterocycle Synthesis via Alkene Difunctionalization = Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation /
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