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Lessons on Caffeine, Cannabis & Co = Plant-derived Drugs and their Interaction with Human Receptors /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Lessons on Caffeine, Cannabis & Co/ by Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf.
其他題名:	Plant-derived Drugs and their Interaction with Human Receptors /
作者:	Böttger, Angelika.
其他作者:	Vothknecht, Ute.
面頁冊數:	X, 217 p. 69 illus., 50 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Pharmacology. -
電子資源:	https://doi.org/10.1007/978-3-319-99546-5
ISBN:	9783319995465

Lessons on Caffeine, Cannabis & Co = Plant-derived Drugs and their Interaction with Human Receptors /
Böttger, Angelika.

Lessons on Caffeine, Cannabis & CoPlant-derived Drugs and their Interaction with Human Receptors /[electronic resource] :by Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf. - 1st ed. 2018. - X, 217 p. 69 illus., 50 illus. in color.online resource. - Learning Materials in Biosciences,2509-6125. - Learning Materials in Biosciences,1.

Introduction: Plant secondary metabolites and their general function in plants -- Historical and current perspective -- Medicinal use -- Recreational use -- General overview over biosynthesis pathways of plant secondary metabolites -- Drugs affecting GPCR: GPCRs in plants and animals -- Dopamine and 5-HT2A-serotonin receptors – Cocaine, mescaline, psilobin -- Opiate receptors – morphine, salvinorin A -- Cannabinoid receptors – THC -- Muscarinergic acetylcholin receptor - muscarin, atropine -- Adenosine receptor – caffeine -- Drugs affecting ion channels: Ligand and voltage activated channels -- Nicotinic acetylcholin receptor – Nicotine, Curare -- GABAA/C-receptor – Muscimol, thujone -- ionotropic Glycine receptor – Strychnine -- ionotropic Glutamate receptor - ibogtenic acid, kainic acid -- TRP channels – capsaicin, menthol, aconitine, resiniferatoxin -- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants -- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan) -- Topoisomerase - camptothecin, etoposide -- G2/M phase arrest, apoptosis – curcubitacin, triptolide.

This textbook provides a structured, easy to understand and thorough insight into the mode of function of plant secondary metabolites in plants and humans. It explains the biosynthesis and molecular action of nicotine, cannabis, caffeine and Co, describes the effects of these drugs on signal transduction at receptors and ion channels in animals, their relevance for human health and their potential for recreational use and abuse. It also offers a broad and comprehensive understanding on the role and function of these diverse molecules for the plants that make them. This textbook is written for master students and scientist in biochemistry and biology as well as for pharmaceutical and medical students. It will be a valuable study tool for teachers and students alike.

ISBN: 9783319995465

Standard No.: 10.1007/978-3-319-99546-5doiSubjects--Topical Terms:

583819
Pharmacology.

LC Class. No.: RM1-950

Dewey Class. No.: 615

Lessons on Caffeine, Cannabis & Co = Plant-derived Drugs and their Interaction with Human Receptors /
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