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Mid-size Drugs Based on Peptides and...
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Mid-size Drugs Based on Peptides and Peptidomimetics = A New Drug Category /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Mid-size Drugs Based on Peptides and Peptidomimetics/ by Hirokazu Tamamura, Takuya Kobayakawa, Nami Ohashi.
其他題名:
A New Drug Category /
作者:
Tamamura, Hirokazu.
其他作者:
Kobayakawa, Takuya.
面頁冊數:
XVII, 100 p. 40 illus., 32 illus. in color.online resource. :
Contained By:
Springer Nature eBook
標題:
Medicinal chemistry. -
電子資源:
https://doi.org/10.1007/978-981-10-7691-6
ISBN:
9789811076916
Mid-size Drugs Based on Peptides and Peptidomimetics = A New Drug Category /
Tamamura, Hirokazu.
Mid-size Drugs Based on Peptides and Peptidomimetics
A New Drug Category /[electronic resource] :by Hirokazu Tamamura, Takuya Kobayakawa, Nami Ohashi. - 1st ed. 2018. - XVII, 100 p. 40 illus., 32 illus. in color.online resource. - SpringerBriefs in Pharmaceutical Science & Drug Development,1864-8118. - SpringerBriefs in Pharmaceutical Science & Drug Development,.
1. Introduction of Mid-Size Drugs and Peptidomimetics -- 2. Chloroalkene Dipeptide Isosteres as Peptidomimetics -- 3. Conformational-restricted Cyclic Peptides -- 4. Peptidomimetics that Mimic Secondary Structures of Peptides -- 5.Peptidomimetics that Mimic Tertiary Structures of Peptides -- 6. Conjugated Compounds Involving Peptides -- 7. Summary and Future Perspectives of Researches on Mid-Size Drugs.
This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Peptides are important biological molecules and have various physiological actions. Peptide-based drug discovery may help bring about the development of useful medicines that are highly safe and show potent pharmacological effects in small doses. Recently, it has been shown that there is an important drug-like space in the mid-sized region between low- and high-molecular-weight compounds. Thus, mid-size drugs such as peptide compounds are being focused on. To date, several peptidomimetics that mimic primary, secondary, and tertiary structures of peptides have been developed to maintain and improve biological activities and actions of peptides. In this book, the features and advantages of mid-size drugs are described in detail. In addition, the merits of utilizing peptidomimetics in the development of mid-size drugs are referred to. Understanding such peptide-derived mid-size drugs will lead to a comprehensive expansion of medicinal chemistry.
ISBN: 9789811076916
Standard No.: 10.1007/978-981-10-7691-6doiSubjects--Topical Terms:
1253747
Medicinal chemistry.
LC Class. No.: RS400-431
Dewey Class. No.: 615.19
Mid-size Drugs Based on Peptides and Peptidomimetics = A New Drug Category /
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