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Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill/ edited by Andrew A. Udy, Jason A. Roberts, Jeffrey Lipman.
other author:	Udy, Andrew A.
Description:	X, 275 p. 22 illus., 9 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Pharmacotherapy. -
Online resource:	https://doi.org/10.1007/978-981-10-5336-8
ISBN:	9789811053368

Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill
Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill[electronic resource] /edited by Andrew A. Udy, Jason A. Roberts, Jeffrey Lipman. - 1st ed. 2018. - X, 275 p. 22 illus., 9 illus. in color.online resource.

1. Basic Pharmacokinetic Principles -- 2. Antibiotic Pharmacodynamics -- 3. Physiological Manifestations of Critical Illness -- 4. Dosing in Obese Critically Ill Patients -- 5. Hypoalbuminemia and Altered Protein Binding -- 6. Antibacterial Pharmacokinetic/Pharmacodynamic Considerations in the Critically ill -- 7. Augmented Renal Clearance -- 8. Antibiotic Dosing During Extracorporeal Membrane Oxygenation -- 9. Therapeutic Drug Monitoring: More than Avoiding Toxicity -- 10. Generic and Optimised Antibacterial Dosing Strategies in the Critically Ill -- 11. Antifungal PK/PD in the Critically Ill -- 12. Antibiotic Dosing in Pediatric Critically Ill Patients -- 13. Antibiotic Stewardship in the Intensive Care Unit.

This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.

ISBN: 9789811053368

Standard No.: 10.1007/978-981-10-5336-8doiSubjects--Topical Terms:

973587
Pharmacotherapy.

LC Class. No.: RM121

Dewey Class. No.: 615.1

Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill
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