國立虎尾科技大學 |

Cellular and Molecular Toxicology of Nanoparticles

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Cellular and Molecular Toxicology of Nanoparticles/ edited by Quaiser Saquib, Mohammad Faisal, Abdulaziz A. Al-Khedhairy, Abdulrahman A. Alatar.
other author:	Saquib, Quaiser.
Description:	XVI, 346 p. 85 illus., 74 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Cell biology. -
Online resource:	https://doi.org/10.1007/978-3-319-72041-8
ISBN:	9783319720418

Cellular and Molecular Toxicology of Nanoparticles
Cellular and Molecular Toxicology of Nanoparticles[electronic resource] /edited by Quaiser Saquib, Mohammad Faisal, Abdulaziz A. Al-Khedhairy, Abdulrahman A. Alatar. - 1st ed. 2018. - XVI, 346 p. 85 illus., 74 illus. in color.online resource. - Advances in Experimental Medicine and Biology,10480065-2598 ;. - Advances in Experimental Medicine and Biology,889.

This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”. The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.

ISBN: 9783319720418

Standard No.: 10.1007/978-3-319-72041-8doiSubjects--Topical Terms:

1253486
Cell biology.

LC Class. No.: QH573-671

Dewey Class. No.: 571.6

Cellular and Molecular Toxicology of Nanoparticles
LDR:03332nam a22003975i 4500 001 996071
003 DE-He213
005 20200703005733.0
007 cr nn 008mamaa
008 201225s2018 gw | s |||| 0|eng d
020 $a 9783319720418 $9 978-3-319-72041-8
024 7 $a 10.1007/978-3-319-72041-8 $2 doi
035 $a 978-3-319-72041-8
050 4 $a QH573-671
072 7 $a PSF $2 bicssc
072 7 $a SCI049000 $2 bisacsh
072 7 $a PSF $2 thema
082 0 4 $a 571.6 $2 23
245 1 0 $a Cellular and Molecular Toxicology of Nanoparticles $h [electronic resource] / $c edited by Quaiser Saquib, Mohammad Faisal, Abdulaziz A. Al-Khedhairy, Abdulrahman A. Alatar.
250 $a 1st ed. 2018.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a XVI, 346 p. 85 illus., 74 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Advances in Experimental Medicine and Biology, $x 0065-2598 ; $v 1048
520 $a This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”. The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.
650 0 $a Cell biology. $3 1253486
650 0 $a Nanotechnology. $3 557660
650 0 $a Biology—Technique. $3 1256859
650 1 4 $a Cell Biology. $3 593889
650 2 4 $a Biological Techniques. $3 678565
700 1 $a Saquib, Quaiser. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1282982
700 1 $a Faisal, Mohammad. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1201685
700 1 $a Al-Khedhairy, Abdulaziz A. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1282984
700 1 $a Alatar, Abdulrahman A. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1282983
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319720401
776 0 8 $i Printed edition: $z 9783319720425
776 0 8 $i Printed edition: $z 9783030101503
830 0 $a Advances in Experimental Medicine and Biology, $x 0065-2598 ; $v 889 $3 1253792
856 4 0 $u https://doi.org/10.1007/978-3-319-72041-8
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)