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Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics/ by Ravichandran Manisekaran.
作者:	Manisekaran, Ravichandran.
面頁冊數:	XL, 168 p. 91 illus., 84 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Biomedical engineering. -
電子資源:	https://doi.org/10.1007/978-3-319-67609-8
ISBN:	9783319676098

Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics
Manisekaran, Ravichandran.

Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics[electronic resource] /by Ravichandran Manisekaran. - 1st ed. 2018. - XL, 168 p. 91 illus., 84 illus. in color.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.

Introduction to Nanomedicine and Cancer Therapy -- Literature Survey on Magnetic, Gold and Core-Shell Nanoparticles -- Characterization Techniques, Cell Cultivation and Experimental Setup -- Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-delivery and Apoptosis Induction in Cancer Cells -- Multiple Iterative Seeding of Surface Plasmon Enhanced Cobalt-Iron Oxide Nanokernels for Cancer Theranostics -- Nano-flotillas MnFe2O4@Au Core-shell Nanoparticles: An Efficient MRI Contrast Agent, Magneto-hyperthermal and Drug-delivery Armada for Cancer -- Concluding Remarks and Future Prospects.

This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.

ISBN: 9783319676098

Standard No.: 10.1007/978-3-319-67609-8doiSubjects--Topical Terms:

588770
Biomedical engineering.

LC Class. No.: R856-857

Dewey Class. No.: 610.28

Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics
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