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Histiocytic Disorders

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Histiocytic Disorders/ edited by Oussama Abla, Gritta Janka.
其他作者:	Abla, Oussama.
面頁冊數:	XII, 392 p. 96 illus., 74 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Hematology. -
電子資源:	https://doi.org/10.1007/978-3-319-59632-7
ISBN:	9783319596327

Histiocytic Disorders
Histiocytic Disorders[electronic resource] /edited by Oussama Abla, Gritta Janka. - 1st ed. 2018. - XII, 392 p. 96 illus., 74 illus. in color.online resource.

Pathology of Histiocytic Disorders and Neoplasms and Related Disorders -- Biology and Genomics of LCH and Related Disorders -- Epidemiology and Clinical Manifestations of Langerhans Cell Histiocytosis in Children -- Central Nervous System Langerhans Cell Histiocytosis -- First-line Treatment of Pediatric Langerhans Cell Histiocytosis -- Treatment of Relapsed and Refractory Langerhans Cell Histiocytosis in Children -- Adult Langerhans Cell Histiocytosis -- Late Effects of Langerhans Cell Histiocytosis and the Association of LCH with Malignancy -- Classification, Clinical Manifestations and Diagnostics of HLH -- CNS involvement in HLH (CNS-HLH) -- Genetics and Pathogenesis of Haemophagocytic Lymphohistiocytosis -- Hemophagocytic Lymphohistiocytosis Associated with Malignancies and with Epstein Barr Virus -- Macrophage Activation Syndrome in Rheumatic Diseases (MAS-HLH) -- Treatment of Newly Diagnosed HLH and Refractory Disease -- Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosis -- HLH in Adults -- Juvenile Xanthogranuloma and Related Non-LCH Disorders -- Erdheim-Chester Disease -- Rosai-Dorfman Disease -- Malignant Histiocytoses.

This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.

ISBN: 9783319596327

Standard No.: 10.1007/978-3-319-59632-7doiSubjects--Topical Terms:

645254
Hematology.

LC Class. No.: RB45

Dewey Class. No.: 616.15

Histiocytic Disorders
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