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Amorphous Drugs = Benefits and Challenges /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Amorphous Drugs/ by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch.
其他題名:	Benefits and Challenges /
作者:	Rams-Baron, Marzena.
其他作者:	Jachowicz, Renata.
面頁冊數:	IX, 230 p. 69 illus., 48 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Medicinal chemistry. -
電子資源:	https://doi.org/10.1007/978-3-319-72002-9
ISBN:	9783319720029

Amorphous Drugs = Benefits and Challenges /
Rams-Baron, Marzena.

Amorphous DrugsBenefits and Challenges /[electronic resource] :by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch. - 1st ed. 2018. - IX, 230 p. 69 illus., 48 illus. in color.online resource.

Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.

This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products. .

ISBN: 9783319720029

Standard No.: 10.1007/978-3-319-72002-9doiSubjects--Topical Terms:

1253747
Medicinal chemistry.

LC Class. No.: RS400-431

Dewey Class. No.: 615.19

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