Language:
English
繁體中文
Help
Login
Back
Switch To:
Labeled
|
MARC Mode
|
ISBD
Current Advances in the Science of O...
~
SpringerLink (Online service)
Current Advances in the Science of Osteosarcoma = Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models /
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Current Advances in the Science of Osteosarcoma/ edited by Eugenie S. Kleinerman, Richard Gorlick.
Reminder of title:
Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models /
other author:
Kleinerman, Eugenie S.
Description:
XIII, 233 p. 34 illus., 23 illus. in color.online resource. :
Contained By:
Springer Nature eBook
Subject:
Cancer research. -
Online resource:
https://doi.org/10.1007/978-3-030-43085-6
ISBN:
9783030430856
Current Advances in the Science of Osteosarcoma = Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models /
Current Advances in the Science of Osteosarcoma
Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models /[electronic resource] :edited by Eugenie S. Kleinerman, Richard Gorlick. - 2nd ed. 2020. - XIII, 233 p. 34 illus., 23 illus. in color.online resource. - Advances in Experimental Medicine and Biology,12580065-2598 ;. - Advances in Experimental Medicine and Biology,889.
The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies -- Genomics and the Immune Landscape of Osteosarcoma -- RECQ DNA Helicases and Osteosarcoma -- Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma -- Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma -- Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response -- Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma -- Wnt Signaling in Osteosarcoma -- Receptor Tyrosine Kinases in Osteosarcoma: 2019 update -- The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets -- Autophagy in OS -- Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs -- Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment -- Comparative Immunology and Immunotherapy of Canine Osteosarcoma -- Index.
This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.
ISBN: 9783030430856
Standard No.: 10.1007/978-3-030-43085-6doiSubjects--Topical Terms:
1253664
Cancer research.
LC Class. No.: RC261-271
Dewey Class. No.: 614.5999
Current Advances in the Science of Osteosarcoma = Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models /
LDR
:03875nam a22004095i 4500
001
1021948
003
DE-He213
005
20200807094806.0
007
cr nn 008mamaa
008
210318s2020 gw | s |||| 0|eng d
020
$a
9783030430856
$9
978-3-030-43085-6
024
7
$a
10.1007/978-3-030-43085-6
$2
doi
035
$a
978-3-030-43085-6
050
4
$a
RC261-271
072
7
$a
MJCL
$2
bicssc
072
7
$a
MED062000
$2
bisacsh
072
7
$a
MJCL
$2
thema
082
0 4
$a
614.5999
$2
23
245
1 0
$a
Current Advances in the Science of Osteosarcoma
$h
[electronic resource] :
$b
Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models /
$c
edited by Eugenie S. Kleinerman, Richard Gorlick.
250
$a
2nd ed. 2020.
264
1
$a
Cham :
$b
Springer International Publishing :
$b
Imprint: Springer,
$c
2020.
300
$a
XIII, 233 p. 34 illus., 23 illus. in color.
$b
online resource.
336
$a
text
$b
txt
$2
rdacontent
337
$a
computer
$b
c
$2
rdamedia
338
$a
online resource
$b
cr
$2
rdacarrier
347
$a
text file
$b
PDF
$2
rda
490
1
$a
Advances in Experimental Medicine and Biology,
$x
0065-2598 ;
$v
1258
505
0
$a
The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies -- Genomics and the Immune Landscape of Osteosarcoma -- RECQ DNA Helicases and Osteosarcoma -- Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma -- Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma -- Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response -- Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma -- Wnt Signaling in Osteosarcoma -- Receptor Tyrosine Kinases in Osteosarcoma: 2019 update -- The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets -- Autophagy in OS -- Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs -- Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment -- Comparative Immunology and Immunotherapy of Canine Osteosarcoma -- Index.
520
$a
This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.
650
0
$a
Cancer research.
$3
1253664
650
0
$a
Medical microbiology.
$3
583124
650
0
$a
Cell biology.
$3
1253486
650
0
$a
Pediatrics.
$3
644839
650
1 4
$a
Cancer Research.
$3
668358
650
2 4
$a
Medical Microbiology.
$3
668401
650
2 4
$a
Cell Biology.
$3
593889
700
1
$a
Kleinerman, Eugenie S.
$e
editor.
$4
edt
$4
http://id.loc.gov/vocabulary/relators/edt
$3
1315526
700
1
$a
Gorlick, Richard.
$e
editor.
$4
edt
$4
http://id.loc.gov/vocabulary/relators/edt
$3
1315527
710
2
$a
SpringerLink (Online service)
$3
593884
773
0
$t
Springer Nature eBook
776
0 8
$i
Printed edition:
$z
9783030430849
776
0 8
$i
Printed edition:
$z
9783030430863
776
0 8
$i
Printed edition:
$z
9783030430870
830
0
$a
Advances in Experimental Medicine and Biology,
$x
0065-2598 ;
$v
889
$3
1253792
856
4 0
$u
https://doi.org/10.1007/978-3-030-43085-6
912
$a
ZDB-2-SBL
912
$a
ZDB-2-SXB
950
$a
Biomedical and Life Sciences (SpringerNature-11642)
950
$a
Biomedical and Life Sciences (R0) (SpringerNature-43708)
based on 0 review(s)
Multimedia
Reviews
Add a review
and share your thoughts with other readers
Export
pickup library
Processing
...
Change password
Login