國立虎尾科技大學 |

Circadian clock and aging

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Circadian clock and aging/ by Syed Ibrahim Rizvi, Gaurav Majumdar.
Author:	Rizvi, Syed Ibrahim.
other author:	Majumdar, Gaurav.
Published:	Singapore :Springer Nature Singapore : : 2024.,
Description:	xii, 204 p. :ill. (chiefly color), digital ; : 24 cm.;
Contained By:	Springer Nature eBook
Subject:	Circadian rhythms. -
Online resource:	https://doi.org/10.1007/978-981-97-6695-6
ISBN:	9789819766956

Circadian clock and aging
Rizvi, Syed Ibrahim.

Circadian clock and aging[electronic resource] /by Syed Ibrahim Rizvi, Gaurav Majumdar. - Singapore :Springer Nature Singapore :2024. - xii, 204 p. :ill. (chiefly color), digital ;24 cm.

1. Introduction to Circadian Rhythms -- 2. Mechanisms of Circadian Oscillations -- 3. Light Sensitivity of the Biological Clock -- 4. Circadian System and Aging in Rodent Models -- 5. Circadian Control of Mitochondrial Dynamics and Its Implication in Aging -- 6. Health Consequences of Circadian Disruption in Humans and Animal Models during aging -- 7. The Human SCN in Health and Age-related Neurological Disorders -- 8. The Circadian Clock as a drug target for anti-aging strategies.

This book aims to understand the inherent circadian cycles of biological processes and their role in maintaining health and healing a variety of diseases. The book is divided into eight sections. The first section introduces circadian rhythms and aging. The second section focuses on the detailed mechanistic approach of oscillatory pathways in mammals. The next section summarizes the sensitivity of the biological clock towards light and the circadian response to melatonin in mammals. The fourth section addresses the circadian architecture at the cellular level and introduces an age-dependent experimental model of rodents for subsequent biochemical and molecular investigations. The subsequent section covers the complexity of circadian regulation in mitochondrial dynamics and its impact on aging. The sixth section of the book discusses the findings obtained from different experimental approaches as a critical threat to the functioning of clock regulatory mechanisms and its associated health consequences during aging in humans and animal models. The circadian oscillatory mechanisms that are dysregulated and might play an important role in the development and progression of neurological disorders such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Huntington's Disease (HD), and Amyotrophic Lateral Sclerosis (ALS), etc are discussed in the next section. Towards the end, the book explores the circadian clock as a possible drug target to restore circadian oscillations.

ISBN: 9789819766956

Standard No.: 10.1007/978-981-97-6695-6doiSubjects--Topical Terms:

583582
Circadian rhythms.

LC Class. No.: QP84.6

Dewey Class. No.: 612.022

Circadian clock and aging
LDR:02965nam a2200325 a 4500 001 1138085
003 DE-He213
005 20241015125734.0
006 m d
007 cr nn 008maaau
008 250117s2024 si s 0 eng d
020 $a 9789819766956 $q (electronic bk.)
020 $a 9789819766949 $q (paper)
024 7 $a 10.1007/978-981-97-6695-6 $2 doi
035 $a 978-981-97-6695-6
040 $a GP $c GP
041 0 $a eng
050 4 $a QP84.6
072 7 $a PSA $2 bicssc
072 7 $a SCI072000 $2 bisacsh
072 7 $a PSA $2 thema
082 0 4 $a 612.022 $2 23
090 $a QP84.6 $b .R627 2024
100 1 $a Rizvi, Syed Ibrahim. $3 1210157
245 1 0 $a Circadian clock and aging $h [electronic resource] / $c by Syed Ibrahim Rizvi, Gaurav Majumdar.
260 $a Singapore : $c 2024. $b Springer Nature Singapore : $b Imprint: Springer,
300 $a xii, 204 p. : $b ill. (chiefly color), digital ; $c 24 cm.
505 0 $a 1. Introduction to Circadian Rhythms -- 2. Mechanisms of Circadian Oscillations -- 3. Light Sensitivity of the Biological Clock -- 4. Circadian System and Aging in Rodent Models -- 5. Circadian Control of Mitochondrial Dynamics and Its Implication in Aging -- 6. Health Consequences of Circadian Disruption in Humans and Animal Models during aging -- 7. The Human SCN in Health and Age-related Neurological Disorders -- 8. The Circadian Clock as a drug target for anti-aging strategies.
520 $a This book aims to understand the inherent circadian cycles of biological processes and their role in maintaining health and healing a variety of diseases. The book is divided into eight sections. The first section introduces circadian rhythms and aging. The second section focuses on the detailed mechanistic approach of oscillatory pathways in mammals. The next section summarizes the sensitivity of the biological clock towards light and the circadian response to melatonin in mammals. The fourth section addresses the circadian architecture at the cellular level and introduces an age-dependent experimental model of rodents for subsequent biochemical and molecular investigations. The subsequent section covers the complexity of circadian regulation in mitochondrial dynamics and its impact on aging. The sixth section of the book discusses the findings obtained from different experimental approaches as a critical threat to the functioning of clock regulatory mechanisms and its associated health consequences during aging in humans and animal models. The circadian oscillatory mechanisms that are dysregulated and might play an important role in the development and progression of neurological disorders such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Huntington's Disease (HD), and Amyotrophic Lateral Sclerosis (ALS), etc are discussed in the next section. Towards the end, the book explores the circadian clock as a possible drug target to restore circadian oscillations.
650 0 $a Circadian rhythms. $3 583582
650 0 $a Aging. $3 559847
650 1 4 $a Ageing. $3 1365964
650 2 4 $a Cellular Circadian Rhythms. $3 1454805
650 2 4 $a Diseases. $3 636013
700 1 $a Majumdar, Gaurav. $3 1461690
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-981-97-6695-6
950 $a Biomedical and Life Sciences (SpringerNature-11642)