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Wildlife Disease From a Fungal Perspective : = A Look Into Host Specificity and Physiology of Ophidiomyes ophiodiicola and Nannizziopsis guarroi.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Wildlife Disease From a Fungal Perspective :/
Reminder of title:	A Look Into Host Specificity and Physiology of Ophidiomyes ophiodiicola and Nannizziopsis guarroi.
Author:	Gentry, Savannah.
Description:	1 online resource (103 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 85-02, Section: B.
Contained By:	Dissertations Abstracts International85-02B.
Subject:	Biology. -
Online resource:	click for full text (PQDT)
ISBN:	9798380094658

Wildlife Disease From a Fungal Perspective : = A Look Into Host Specificity and Physiology of Ophidiomyes ophiodiicola and Nannizziopsis guarroi.
Gentry, Savannah.

Wildlife Disease From a Fungal Perspective :A Look Into Host Specificity and Physiology of Ophidiomyes ophiodiicola and Nannizziopsis guarroi. - 1 online resource (103 pages)

Source: Dissertations Abstracts International, Volume: 85-02, Section: B.

Thesis (Ph.D.)--The University of Wisconsin - Madison, 2023.

Includes bibliographical references

In this dissertation, I lean heavily on the concept of host specificity toward broadening our understanding of fungal physiology in wildlife diseases. I use the understudied fungi Ophidiomyces ophiodiicola and Nannizziopsis guarroi to enhance the body of literature around the emerging infectious diseases they cause, snake fungal disease and yellow fungus disease, respectively. Each chapter relates its findings to concerns of infectious disease escaping into naive wildlife populations that could result in potentially unforeseen and long-lasting consequences for a species.In chapter I, I investigated the pervasive literature assumptions between N. guarroi and its associated host, bearded dragons. Specifically, I studied the requirements that consider a fungal pathogen as a direct, primary, infection agent as opposed to an opportunistic, secondary infection agent. Following Koch's postulates, we confirmed N. guarroi could establish an infection in healthy bearded dragons without the necessity of an abrasion, supporting literature assumptions with experimental evidence. In chapter II, I reexamined the host species for both O. ophiodiicola and N. guarroi known to be snakes and lizards, respectively. Based on the shared fungal history of these pathogens being a part of the former Chrysosporium anamorph of Nannizziopsis vriesii (CANV), I focused on the ability of each fungus to infect the opposite host. I was in part driven to understand if either fungus was truly restricted to their documented hosts. We found evidence that both O. ophiodiicola and N. guarroi could establish infection in both snakes and lizards, ultimately increasing the host range of each disease and the concern for an increased disease distribution.In chapter III, I am the first to assemble the genome of N. guarroi for a suite of putative genes related to keratin degradation. I focus on the observed ability of N. guarroi to infect reptiles without disruptions in the epidermis, identifying the presence of enzymatic tools that could unveil downstream pathogenicity factors and differ from other fungi once a part of the CANV complex.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798380094658Subjects--Topical Terms:

599573
Biology.
Subjects--Index Terms:

MycologyIndex Terms--Genre/Form:

554714
Electronic books.

Wildlife Disease From a Fungal Perspective : = A Look Into Host Specificity and Physiology of Ophidiomyes ophiodiicola and Nannizziopsis guarroi.
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