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Genomics Applied to Conservation of Genetic Diversity in Dutch Livestock.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Genomics Applied to Conservation of Genetic Diversity in Dutch Livestock./
Author:	Hulsegge, Ina.
Description:	1 online resource (167 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 85-08, Section: A.
Contained By:	Dissertations Abstracts International85-08A.
Subject:	Breeding of animals. -
Online resource:	click for full text (PQDT)
ISBN:	9798381451931

Genomics Applied to Conservation of Genetic Diversity in Dutch Livestock.
Hulsegge, Ina.

Genomics Applied to Conservation of Genetic Diversity in Dutch Livestock. - 1 online resource (167 pages)

Source: Dissertations Abstracts International, Volume: 85-08, Section: A.

Thesis (Ph.D.)--Wageningen University and Research, 2023.

Includes bibliographical references

Conserving genetic diversity is essential for the sustainability of populations. In livestock, the amount of genetic diversity should be large enough to enable the adaptation of populations to changing environments and market requirements, and for selection to genetically improve economically important traits. Unfortunately, the current trend in populations is often for reduced genetic diversity due to intense selection or random drift. Consequently, breeding methods and gene banks were developed to avoid the risk of losing genetic diversity. As genomic information becomes more accessible, we now have the option to better manage genetic diversity. In this thesis, I applied genomics to conservation practises. More specifically, I applied genomic tools and methods to prove their relevance for the conservation of Dutch livestock breeds. I demonstrated that the use of genomics led to a more detailed understanding of the genetic diversity conserved in gene banks or in living populations of numerically small breeds in The Netherlands. Moreover, I reported the implications for genetic diversity of (1) lines or supposed lines within a numerically small breed, (2) merging and terminating lines of the Dutch Landrace pig breed, and (3) the replacement over time of traditional local cattle breed (Dutch Friesian Cattle) with just productive breed (Holstein Friesian). Subsequently, I illustrated that only a small set of informative SNPs is needed to differentiate among Dutch local cattle breeds. Using such a small set of informative SNPs a genetic tool (DNA test) was developed for the determination of breed purity of cattle. Lastly, I addressed the recent developments in genomics and how they can be used effectively for genetic conservation, and in particular how gene banks can benefit from these developments, and I outline possible future directions for (a more effective) conservation of breeds using genomic methods. More specially, I propose a strategy for conservation and stated that gene banks should transform from "traditional gene banks" into "digital gene banks".

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798381451931Subjects--Topical Terms:

1476166
Breeding of animals.
Index Terms--Genre/Form:

554714
Electronic books.

Genomics Applied to Conservation of Genetic Diversity in Dutch Livestock.
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245 1 0 $a Genomics Applied to Conservation of Genetic Diversity in Dutch Livestock.
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300 $a 1 online resource (167 pages)
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500 $a Source: Dissertations Abstracts International, Volume: 85-08, Section: A.
500 $a Advisor: Veerkamp, Roel F.;Windig, Jack J.;Bouwman, Aniek C.
502 $a Thesis (Ph.D.)--Wageningen University and Research, 2023.
504 $a Includes bibliographical references
520 $a Conserving genetic diversity is essential for the sustainability of populations. In livestock, the amount of genetic diversity should be large enough to enable the adaptation of populations to changing environments and market requirements, and for selection to genetically improve economically important traits. Unfortunately, the current trend in populations is often for reduced genetic diversity due to intense selection or random drift. Consequently, breeding methods and gene banks were developed to avoid the risk of losing genetic diversity. As genomic information becomes more accessible, we now have the option to better manage genetic diversity. In this thesis, I applied genomics to conservation practises. More specifically, I applied genomic tools and methods to prove their relevance for the conservation of Dutch livestock breeds. I demonstrated that the use of genomics led to a more detailed understanding of the genetic diversity conserved in gene banks or in living populations of numerically small breeds in The Netherlands. Moreover, I reported the implications for genetic diversity of (1) lines or supposed lines within a numerically small breed, (2) merging and terminating lines of the Dutch Landrace pig breed, and (3) the replacement over time of traditional local cattle breed (Dutch Friesian Cattle) with just productive breed (Holstein Friesian). Subsequently, I illustrated that only a small set of informative SNPs is needed to differentiate among Dutch local cattle breeds. Using such a small set of informative SNPs a genetic tool (DNA test) was developed for the determination of breed purity of cattle. Lastly, I addressed the recent developments in genomics and how they can be used effectively for genetic conservation, and in particular how gene banks can benefit from these developments, and I outline possible future directions for (a more effective) conservation of breeds using genomic methods. More specially, I propose a strategy for conservation and stated that gene banks should transform from "traditional gene banks" into "digital gene banks".
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2024
538 $a Mode of access: World Wide Web
650 4 $a Breeding of animals. $3 1476166
650 4 $a Livestock. $3 946845
650 4 $a Dairy cattle. $3 1476167
650 4 $a Endangered & extinct species. $3 1465262
650 4 $a Decision making. $3 528319
650 4 $a Farms. $3 1251033
650 4 $a Genetic engineering. $3 592227
650 4 $a Genomes. $3 600075
650 4 $a Gene banks. $3 1476168
650 4 $a Genomics. $3 578973
650 4 $a Genetic diversity. $3 1465315
650 4 $a Agriculture. $3 660421
650 4 $a Animal sciences. $3 1178863
650 4 $a Bioengineering. $3 598252
650 4 $a Genetics. $3 578972
650 4 $a Wildlife conservation. $3 654486
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690 $a 0475
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710 2 $a Wageningen University and Research. $3 1372529
773 0 $t Dissertations Abstracts International $g 85-08A.
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30775114 $z click for full text (PQDT)