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Complex structure and dynamics of the heart

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Complex structure and dynamics of the heart/ by Philip Bittihn.
Author:	Bittihn, Philip.
Published:	Cham :Springer International Publishing : : 2015.,
Description:	xv, 204 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Heart - Anatomy. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-12232-8
ISBN:	9783319122328 (electronic bk.)

Complex structure and dynamics of the heart
Bittihn, Philip.

Complex structure and dynamics of the heart[electronic resource] /by Philip Bittihn. - Cham :Springer International Publishing :2015. - xv, 204 p. :ill. (some col.), digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

Introduction -- Methods -- Results -- Conclusion -- Appendix A Modeling Details -- Appendix B Supplementary Data -- Appendix C MediaSim -- An Open Framework for Simulating Extended Systems -- Index.

This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock currently the only reliable way to terminate life-threatening fibrillation by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias.

ISBN: 9783319122328 (electronic bk.)

Standard No.: 10.1007/978-3-319-12232-8doiSubjects--Topical Terms:

796610
Heart
--Anatomy.

LC Class. No.: QM181

Dewey Class. No.: 611.12

Complex structure and dynamics of the heart
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505 0 $a Introduction -- Methods -- Results -- Conclusion -- Appendix A Modeling Details -- Appendix B Supplementary Data -- Appendix C MediaSim -- An Open Framework for Simulating Extended Systems -- Index.
520 $a This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock currently the only reliable way to terminate life-threatening fibrillation by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias.
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