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Protein homology detection through a...
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SpringerLink (Online service)
Protein homology detection through alignment of Markov random fields = using MRFalign /
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Protein homology detection through alignment of Markov random fields/ by Jinbo Xu, Sheng Wang, Jianzhu Ma.
Reminder of title:
using MRFalign /
Author:
Xu, Jinbo.
other author:
Wang, Sheng.
Published:
Cham :Springer International Publishing : : 2015.,
Description:
viii, 51 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:
Springer eBooks
Subject:
Markov random fields. -
Online resource:
http://dx.doi.org/10.1007/978-3-319-14914-1
ISBN:
9783319149141 (electronic bk.)
Protein homology detection through alignment of Markov random fields = using MRFalign /
Xu, Jinbo.
Protein homology detection through alignment of Markov random fields
using MRFalign /[electronic resource] :by Jinbo Xu, Sheng Wang, Jianzhu Ma. - Cham :Springer International Publishing :2015. - viii, 51 p. :ill. (some col.), digital ;24 cm. - SpringerBriefs in computer science,2191-5768. - SpringerBriefs in computer science..
Introduction -- Method -- Software -- Experiments and Results -- Conclusion.
This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.
ISBN: 9783319149141 (electronic bk.)
Standard No.: 10.1007/978-3-319-14914-1doiSubjects--Topical Terms:
897937
Markov random fields.
LC Class. No.: QA274.45
Dewey Class. No.: 519.23
Protein homology detection through alignment of Markov random fields = using MRFalign /
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