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Protein therapeutics

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Protein therapeutics/ edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal.
other author:	Vaughan, Tristan.
Published:	Weinheim, Germany :Wiley-VCH, : c2017.,
Description:	1 online resource.
Subject:	Proteins - Therapeutic use. -
Online resource:	https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699124
ISBN:	9783527699124

Protein therapeutics
Protein therapeutics (Wiley-VCH)

Protein therapeutics[electronic resource] /edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal. - 1st ed. - Weinheim, Germany :Wiley-VCH,c2017. - 1 online resource. - Methods and principles in medicinal chemistry ;v. 71a-71b. - Methods and principles in medicinal chemistry ;v. 39..

Includes bibliographical references and index.

In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.

ISBN: 9783527699124

Standard No.: 10.1002/9783527699124doiSubjects--Topical Terms:

778498
Proteins
--Therapeutic use.

LC Class. No.: RM666.P87 / P76 2017

Dewey Class. No.: 615.3

Protein therapeutics
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250 $a 1st ed.
260 $a Weinheim, Germany : $b Wiley-VCH, $c c2017.
300 $a 1 online resource.
490 1 $a Methods and principles in medicinal chemistry ; $v v. 71a-71b
504 $a Includes bibliographical references and index.
520 $a In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.
588 $a Description based on print version record.
650 0 $a Proteins $x Therapeutic use. $3 778498
650 0 $a Protein engineering. $3 669039
650 0 $a Protein drugs. $3 583143
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700 1 $a Vaughan, Tristan. $3 1177522
700 1 $a Osbourn, Jane. $3 1177523
700 1 $a Jallal, Bahija. $3 1026993
830 0 $a Methods and principles in medicinal chemistry ; $v v. 39. $3 964903
856 4 0 $u https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699124