國立虎尾科技大學 |

Sex and gender factors affecting metabolic homeostasis, diabetes and obesity

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Sex and gender factors affecting metabolic homeostasis, diabetes and obesity/ edited by Franck Mauvais-Jarvis.
other author:	Mauvais-Jarvis, Franck.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	xxii, 627 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Sex factors in disease. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-70178-3
ISBN:	9783319701783

Sex and gender factors affecting metabolic homeostasis, diabetes and obesity
Sex and gender factors affecting metabolic homeostasis, diabetes and obesity[electronic resource] /edited by Franck Mauvais-Jarvis. - Cham :Springer International Publishing :2017. - xxii, 627 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.10430065-2598 ;. - Advances in experimental medicine and biology ;780..

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on "Sex and gender factors affecting metabolic homeostasis, diabetes and obesity" to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

ISBN: 9783319701783

Standard No.: 10.1007/978-3-319-70178-3doiSubjects--Topical Terms:

583863
Sex factors in disease.

LC Class. No.: RB212

Dewey Class. No.: 616.008

Sex and gender factors affecting metabolic homeostasis, diabetes and obesity
LDR:02563nam a2200313 a 4500 001 922332
003 DE-He213
005 20171210021134.0
006 m d
007 cr nn 008maaau
008 190624s2017 gw s 0 eng d
020 $a 9783319701783 $q (electronic bk.)
020 $a 9783319701776 $q (paper)
024 7 $a 10.1007/978-3-319-70178-3 $2 doi
035 $a 978-3-319-70178-3
040 $a GP $c GP
041 0 $a eng
050 4 $a RB212
072 7 $a MFG $2 bicssc
072 7 $a MED075000 $2 bisacsh
082 0 4 $a 616.008 $2 23
090 $a RB212 $b .S518 2017
245 0 0 $a Sex and gender factors affecting metabolic homeostasis, diabetes and obesity $h [electronic resource] / $c edited by Franck Mauvais-Jarvis.
260 $a Cham : $c 2017. $b Springer International Publishing : $b Imprint: Springer,
300 $a xxii, 627 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.1043
520 $a The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on "Sex and gender factors affecting metabolic homeostasis, diabetes and obesity" to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.
650 0 $a Sex factors in disease. $3 583863
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Human Physiology. $3 668349
650 2 4 $a Endocrinology. $3 645497
650 2 4 $a Laboratory Medicine. $3 673604
650 2 4 $a Pharmaceutical Sciences/Technology. $3 768561
650 2 4 $a Andrology. $3 676527
650 2 4 $a Gynecology. $3 644094
700 1 $a Mauvais-Jarvis, Franck. $3 1197853
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v 780. $3 881230
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-70178-3
950 $a Biomedical and Life Sciences (Springer-11642)